"Cardiac Bioengineering: 3D Visualization of Myocardial Fiber Disruption and Tissue Engineered Patch Repair"
Jun Liao, Ph.D., Assoc. Professor of Biomedical Engineering, Mississippi State
Abstract: Each year, approximately one million Americans suffer myocardial infarctions (MIs) with a 10% in-hospital mortality rate. Medical interventions are needed for those patients suffering from MIs. The main goal of all the treatments to MIs is preventing the adverse remodeling of the left ventricle that leads to heart failure. In the development of new treatment approaches, there are needs for 3D visualization of the infarcted tissues and customized cardiac repair strategies. In this presentation, two topics are covered: one is 3D visualization of myocardial fiber disruption after acute MI via diffusion tensor magnetic resonance imaging (DT-MRI), the other is cardiac patch tissue engineering based on porcine acellular myocardial scaffolds.