event, known as Chirality 2012, is the foremost conference for all
sciences associated with chirality, one aspect of which is vital to drug
development and other processes. Chiral compounds – such as amino acids and
sugars - are molecules referred to as enantiomers; compounds that differ only
by being non-superimposable mirror images of each other.
in the science of chiral separations, discrimination and synthesis have led to
advances in drug therapy and disease detection. Chiral discrimination is also
used in testing for environmental contaminants and in geochemical dating. Sharing methods and results of recognizing,
synthesizing, manipulating and understanding the characteristics of chiral
molecules are at the heart of the conference.
W. Armstrong, a professor and internationally known chemist who holds the
Robert A. Welch Chair in Chemistry at UT Arlington, has organized Chirality
2012 along with Kevin Schug, an associate professor of chemistry and
biochemistry and the Shimadzu Distinguished Professor of Analytical Chemistry
at UT Arlington.
“We are bringing some of the best organic
chemists, analytical chemists, pharmaceutical scientists, physical scientists,
theoretical scientists and many others together to talk about their latest
research,” said Armstrong. “This is a very broad conference because chirality
encompasses so many areas of science.”
of the highlights planned for the conference include:
lectures by Ron Breslow, Columbia University professor and 1991 U.S. National
Medal of Science Recipient, and E.J. Corey, Harvard University professor and
1990 Nobel Laureate in Chemistry. Breslow will discuss the “Origin of Chirality
on Earth” on Monday, June 11. Corey will speak on Tuesday, June 12 on
“Enantioselective Methods for the Synthesis of Polycycles.”
of the 2012 Chirality Medal to Eric N. Jacobsen, Professor of Chemistry and
Chemical Biology at Harvard University. Jacobsen’s research focuses on
mechanistic and synthetic chemistry and the development of new methods for
session on the “Practice and Consequences of Chiral Drug Development” that will
feature an examination of the science behind chiral drug patent litigation.
pharmaceutical industry job bureau, books signings and a special session for
presentations by young investigators will be featured.
full schedule of scientific sessions and events is online at www.chirality2012.com.
see hosting Chirality 2012 as just one more way that UT Arlington's faculty are
helping to shine a spotlight on North Texas and the important scientific work
going on here," said Ronald L. Elsenbaumer, provost and vice president for
academic affairs at UT Arlington.
of the conference presenters are from outside the U.S., but Armstrong said he
and Schug also sought to include numerous Texas colleagues to represent the
high quality research going on in the Southwest.
example, a team led by Bryan W. Brooks, professor of environmental science and
biomedical studies at Baylor University, will present research on
“Environmental Fate, Effects and Risks of Chiral Contaminants” during a June 11
session on “Stereochemical Effects in the Environment and Drugs.”
Chirality 2012 in North Texas will allow students and local scientists the
opportunity to hear about cutting-edge research in-person, straight from the
people doing it,” Schug said.
generous vendors are supporting the conference. Among the largest
contributors are Chiral Technologies, Sigma-Aldrich, Shimadzu Scientific
Instruments and BioTools, Inc.
this spring, Shimadzu Scientific Instruments gave UT Arlington nearly $3
million in analytical equipment to start the Shimadzu
Center for Advanced Analytical Chemistry. Instruments in the lab are already being used for research
into preventions and treatments for illnesses as cancer and malaria as well as
in the development of nano materials for industry.
The University of Texas at Arlington
is a comprehensive research institution of nearly 33,500 students in the heart
of North Texas. Visit www.uta.edu to learn more.