Linder, S.W., Yanik, G.W and Bobbitt, D. R., Evaluation of Laser-Based Polarimetry for Assessment of Enantiomeric Excess (EE) at the Extremes of the EE Scale, Microchemical Journal, 2004, 76, 105-112.
Category: Refereed Publications
2002
Edkins, T.J., Shah, R.D., Meier, P., Bobbitt, D.R., Saranadasa, H. and Lodevico, R.D., Quantitative Analysis of Incomplete HPLC Resolution of Enantiomers. Fit of Polarimetric Detection for D- and L-Phenylalanine to a Gaussian Function, Enantiomer, 2002, 7, 11-22.
Category: Refereed Publications
2002
Linder, S.W., Yanik, G.W., Francotte, E.R., and Bobbitt, D. R., Real-time Assessment of Enantiomeric Purity via a Polarimetric/Absorption Detector Response Function, Enantiomer, 2002, 7, 41-47.
Category: Refereed Publications
2001
Bobbitt, D.R. and Linder, S.W., Recent Advances in Chiral Detection for High Performance Liquid Chromatography, Trends in Analytical Chemistry, 20, 111-123, 2001.
Category: Refereed Publications
2001
Fry, D.R. and Bobbitt, D. R., Investigation of Dynamically Modified Optical-Fiber Sensors for pH Sensing at the Extremes of the pH Scale, Microchemical Journal, 69, 123-131, 2001.
Category: Refereed Publications
Presentations and Projects
Overview of Research Experience for Undergraduates Site Project in Chemistry and Biochemistry at the University of Arkansas - 2002
Bobbitt, D.R. and Paul, D.W., 223rd National American Chemical Society Meeting, Orlando, FL, April 7-11, 2002.
Assessment of Enantiomeric Excess at Extreme Levels using Laser-Based Polarimetry - 2002
Linder, S.W., Yanik, G.W. and Bobbitt, D.R., 223rd National American Chemical Society Meeting, Orlando, FL, April 7-11, 2002.
Integration of Ru(bpy)33+ - Based Chemiluminescence with Microfabricated CE Devices for the Analysis of Amines, Amino Acids and Proteins - 2002
Waguespack, B.L. and Bobbitt, D.R., 223rd National American Chemical Society Meeting, Orlando, FL, April 7-11, 2002.
Real-Time Assessment of Enantiomeric Purity in Preparative-Scale Separations Using a Combined UV and Polarimetric Detector Response ratio - 2001
Bobbitt, D.R., Linder, S.W. and Yanik, G.W., American Chemical Society National Meeting, San Diego, CA, April 1-6, 2001.
Development and Application of Polarimetric Methods for Process Control and Process-Scale Separations - 2001
Bobbitt, D.R., University of Washington: Center for Process Analytical Chemistry, Seattle, WA, May 6-10, 2001
Advanced Detection in Analytical- and Preparative-Scale High Performance Liquid Chromatography - 2001
Bobbitt, D.R., Chromatography Forum of Delaware Valley, West Chester, PA, June 4, 2001.
Development of New Strategies for Measuring Optical Activity; and Ru(bpy)33+-based Chemiluminescence Detection of Amines and Amino Acids - 2001
Bobbitt, D.R., ViroPharma, Inc., Exton, PA, June 6, 2001.
Tris (2,2’-bipyridyl) Ruthenium III – based Chemiluminescence Detection of Amino Acids: Application to Capillary Electrophoresis and Micro-sequencing - 2001
Bobbitt, D.R. and Waguespack, B.L., Southwest Regional Meeting of the American Chemical Society, San Antonio, TX, October 19, 2001.
Laser-based Polarimetry-Assisted Characterization and Optimization of Analytical and Preparative Scale Enantio-selective Separations - 2000
Bobbitt, D.R. and Linder, S. W., Sensor Technologies: Needs and Assessment Symposium – Development and Integration of Advances in Measurement Technology for Applications in Biotechnology, Pharmaceuticals and Food Safety, Santa Fe, NM, February 28-29, 2000.
Laser-based Polarimetric Detection Can Improve both the Quantitative and Qualitative Analysis of Pharmaceutical Materials - 2000
Yanik, G.W., Bobbitt, D.R. and Linder, S W. 2000 Pittsburgh Conference on Analytical Chemistry, New Orleans, LA, March 12-17, 2000.
Development of Polarimetric Methods for the Assessment and Optimization of Process-scale Chiral Separations - 2000
Yanik, G.W., Bobbitt, D.R. and Linder, S.W., Spring 2000 ACS National Meeting, San Francisco, CA, March 26–30, 2000.
Prep-scale Monitoring of Enantiomeric Purity through the Mathematical Combination of UV and Polarimetric Detectors - 2000
Yanik, G.W., Francotte, E., Bobbitt, D.R. and Linder, S.W., PREP 2000, Washington, D.C., May 14–17, 2000.
Enhanced Qualitative Information via Chiral-Selective Detection in HPLC - 2000
Bobbitt, D.R., Chromatography Forum of Delaware Valley, Philadelphia, PA, June 5, 2000 (INVITED).
Laser-Based Polarimetric Detection Coupled with HPLC: A Synergistic Separation/Detection Approach for Chiral-Selective Analysis - 2000
Yanik, G.W. and Bobbitt, D.R., 24th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC-2000), Seattle, WA, June 24–30, 2000.
Ru(bpy)33+-Based Detection of Tertiary Amines and Its Potential as a New Approach for the Labeling of Proteins and Peptides - 2000
Waguespack, B.L. and Bobbitt, D.R., 24th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC-2000), Seattle, WA, June 24–30, 2000.
Application of the In Situ Electrogenerated Ru(bpy)33+ Based Chemiluminescence Detection Cell in Capillary Electrophoresis and Micellar Electrokinetic Capillary Chromatography - 2000
Wang, X. and Bobbitt, D.R., 24th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC-2000), Seattle, WA, June 24–30, 2000.
Development and Application of Laser-Based Polarimetric Methods for Improved Quantitative and Qualitative Analysis of Pharmaceutical Compounds - 2000
Linder, S.W. and Bobbitt, D.R., 24th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC-2000), Seattle, WA, June 24 30, 2000.
Optical Fiber pH Sensor for Measurments at the Extremes of the pH Scale - 2000
Fry, D.R. and Bobbitt, D.R., 2000 Fall ACS National Meeting, Washington, D.C., August 20–24, 2000.
Analysis of Enantiomers: An Evaluation of Various Measurement Techniques Applied During Incomplete Chromatographic Resolution of Enantiomers using Laser Polarimetric and UV Absorbance Detection - 2000
International Conference on Chiral Discrimination”, Yanik, G.W., Mannschrenck, A., Brandl, F., Bobbitt, D.R. and Linder, S.W., International Conference on Chiral Discrimination, Mont Blanc, France, September 24-28, 2000.
Characterization and Optimization of Chiral-selective Separations using Laser-based Polarimetric Detection - 2000
Bobbitt, D.R. and Yanik, G.W., SPICA 2000, Zurich, Switzerland, October 9–11, 2000
Development of a Novel Polarimetric Method for the Real-time Assessment of Enantiomeric Excess - 2000
Bobbitt, D.R., University of Washington: Center for Process Analytical Chemistry, Seattle WA, November 5–8, 2000 (INVITED).
Use of Laser-Based Polarimetric Detection in Process Control and Quality Assurance Applications - 1999
Bobbitt, D.R., Mosley, B. and Yanik, G.W., 13th International Forum on Process Analytical Chemistry, San Antonio, TX, January24–27, 1999.
Electrogenerated Ru(bpy)33+-Based Chemiluminescence Detection of Biogenic Amines and Amino Acids Following Separation by Capillary Electrophoresis or Micellar Electrokinetic Capillary Chromatography - 1999
Wang, X. and Bobbitt, D.R., 1999 Pittsburgh Conference on Analytical Chemistry, Orlando, FL, March 11–16, 1999.
Use of Laser-Based Polarimetric Detection in Process Control and Quality Assurance Applications - 1999
Bobbitt, D.R., Mosley, B., Yanik, G.W. and Alper, M.S., 1999 Pittsburgh Conference on Analytical Chemistry, Orlando, FL, March 11–16, 1999.
Applications of Circular Dichroism and Polarimetric Detection for Qualitative and Quantitative Analysis in Process Research Applications - 1999
Shah, R.D., Edkins, T.J., Roseman, L.A. and Bobbitt, D.R., 23rd International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC ’99), Granada, Spain, May 4-10, 1999.
Development and Application of Polarimetric Methods for Chiral-Selective Analysis - 1999
Bobbitt, D.R., University of Washington: Center for Process Analytical Chemistry, Seattle, WA, May 3-6, 1999 (INVITED).
Potential of Polarimetric Methods for Enhanced Qualitative and Quantitative Analysis of Pharmaceutical Compounds - 1999
Bobbitt, D.R. and Yanik, G.W., International Symposium on Pharmaceutical and Biomedical Analysis, Washington, D.C., May 9-12, 1999.
Optimization of Chiral Separations using Laser-Based Polarimetric Detection - 1999
Bobbitt, D.R. and Yanik, G.W., 12th International Symposium on Preparative/Process Chromatography and Related Techniques (PREP ’99), San Francisco, CA, May 23-26, 1999 (INVITED).
Advanced Detection in HPLC - 1999
Bobbitt, D.R., Chromatography Forum of Delaware Valley, Philadelphia, PA, June 7, 1999 (INVITED).
Tris (2,2’-bipyridyl)ruthenium III – Based Chemiluminescent Detection of Amino Acids: Application to Capillary Electrophoresis and Microscale Protein Sequencing - 1999
Bobbitt, D.R., Los Alamos National Laboratory, Los Alamos, NM, June 30, 1999 (INVITED).
Laser-Based Polarimetric Detection Provides Improved Quantitation of Chiral Compounds under Conditions of Low Chromatographic Resolution - 1999
Bobbitt, D.R., Yanik, G.W. and Lodevico, R., International Symposium on Chiral Discrimination, Chicago, IL, July 25-28, 1999.
Laser-Based Polarimetry: A Key Technology in the Development and Optimization of Process-Scale Chiral Separations - 1999
Bobbitt, D.R. and Yanik, G.W., ChiraSource ’99, Boston, MA, August 16–19, 1999.
Assesment of Changes in Chemical Environment and Structure of Amino Acids, Peptides and Proteins via Application of Specific Rotation Measurements - 1999
Bobbitt, D.R. and Yanik, G.W., 19th International Symposium on the Separation of Proteins, Peptides and Polynucleotides, Delray Beach, FL, October 31–November 3, 1999.
Applications of Polarimetric Detection in Pharmaceutical Discovery and Development - 1999
Bobbitt, D.R. and Yanik, G.W., Eastern Analytical Symposium, Somerset NJ, November 14– 19, 1999.
Development of a New, Laser-Based Polarimetric Detector and Its Application to High Performance Liquid Chromatography - 1998
Yanik, G.W. and Bobbitt, D.R., 1998 Pittsburgh Conference on Analytical Chemitry, New Orleans, LA, March 1-5, 1998.
New Detection Cell for Electrogenerated Ru(bpy)33+ - based Chemiluminescence Detection in Capillary Electrophoresis and Micellar Electrokinetic Capillary Chromatography - 1998
Wang, X. and Bobbitt, D.R., 1998 International Conference on HPLC, St. Louis, MO, May 9-15, 1998.
Development of a New, Laser-Based Polarimetric Detector and its Application to High Performance Liquid Chromatography - 1998
Yanik, G.W. and Bobbitt, D.R., 1998 International Conference on HPLC, St. Louis, MO, May 9-15, 1998.
Development of a New, Laser-Based Chiral Detector and Its Application to the Analysis of Chiral Compounds - 1998
Yanik, G.W., Bobbitt, D.R. and Alper, M.S., 10th International Symposium on Chiral Discrimination, Vienna, Austria, September 2, 1998.
Chemiluminescent Detection of Amines and Amino Acids After Separation by MEKC; Implications for Pharmaceutical Analysis - 1998
Bobbitt, D.R., Chromatography Forum of Delaware Valley, Media, PA, September 22, 1998 (INVITED).
Use of Polarimetric Methods as an Adjunct to Chiral-Selective Separations - 1998
Bobbitt, D.R., Johnson and Johnson Symposium on Polymers and Biomaterials, Princeton, NJ, September 23, 1998 (INVITED).
On-Line Optical Rotation Measurements Utilizing a New Laser-Based Chiral Detector - 1998
Yanik, G.W., Bobbitt, D.R. and Mosley, B., 1998 Conference on Chiral Technology, Barcelona, Spain, November 9-11, 1998.
Pharmaceutical Applications of a New, Laser-based Chiral Detector - 1998
Bobbitt, D.R., Yanik, G.W. and Alper, M.S., Eastern Analytical Symposium, Somerset, NJ, November 15–20, 1998.
Applications of Laser-based Polarimetric HPLC Detection for Pharmaceutical Analysis - 1997
R. Shah, R., Edkins, T.J. and Bobbitt, D.R., Chiral Conference of the Americas, Cancun, Mexico, June 11, 1997 (INVITED).
pH Sensing at the Extremes of the pH Scale - 1997
Fry, D.R., Hong, Y. and Bobbitt, D.R., 1997 Fall ACS National Meeting, Las Vegas, NV, September 7-11, 1997 (INVITED).
A New Detection Cell for Electrogenerated Ru(bpy)33+ - Based Chemiluminescence Detection in Capillary Electrophoresis - 1997
Wang, X., Lillquist, A. and Bobbitt, D.R., 1997 Fall ACS National Meeting, Las Vegas, NV, September 7-11, 1997.
Application of Capillary Electrophoresis with Ru(bpy)33+ Chemiluminescence Detection to Compounds of Pharmaceutical and Clinical Interest - 1997
Anderson, P.W., Pittman, Z., Lillquist, A. and Bobbitt, D.R., 1997 Fall ACS National Meeting, Las Vegas, NV, September 7-11, 1997.
Development of an Optical Fiber Based pH Sensor for Use in Highly Acidic Solutions - 1997
Fry, D.R., Hong, Y. and Bobbitt, D.R., 1997 Fall ACS National Meeting, Las Vegas, NV, September 7-11, 1997.
Evaluation of Laser-based Polarimetric HPLC Detection for Quantitating Poorly Resolved Enantiomers - 1997
Lodevico, R.G., Bobbitt, D.R., Edkins, T.J. and Shah, R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Providence, RI, October 1997 (INVITED).
Development an Application of Polarimetric Methods for Chiral-Selective Analysis - 1996
Bobbitt, D.R., Analytical Science Symposium: The R.W. Johnson Pharmaceutical Research Institute, Peddlers Village, PA, October 15, 1996 (INVITED).
Advances in Protein Sequencing Methodology Combining Capillary Electrophoresis with Chemiluminescence Detection-Marriage of Convenience or Necessity - 1995
Bobbitt, D.R., University of Washington, Seattle, WA, May 15, 1995 (INVITED).
Enantiomeric Quantitation of Tramadol Hydrochloride without Separation Using Laser-Based Polarimetry - 1995
Edkins, T.J., Bobbitt, D.R. and Rossi, T., HPLC 95, Boston, MA, September 10, 1995.
Enantio-Selective Analysis Based on Polarimetric Detection - 1995
Lodevico, R., Bobbitt, D.R. and Edkins, T.J., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Cincinnati, OH, October 15-20, 1995.
Optical Fiber-Based pH Sensor Using Hydrophobically Associated Fluorescein and Laser-Induced Fluorescence Detection - 1995
McMaughan, S., Wang, Y. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Cincinnati, OH, October 15-20, 1995.
Ru(bpy)33+-Based Detection of Underivatized Amino Acids and Peptides Separated by Capillary Electrophoresis - 1995
Hendrickson, H.D., Pittman, Z. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Cincinnati, OH, October 15-20, 1995.
Maintaining Biospecificity Through Rational Design of Sensing Ligands for Dynamically Modified Reagent Phases - 1995
Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Cincinnati, OH, October 15-20, 1995 (INVITED).
In Situ Generated Chemiluminescence Detection of Underivatized Amino Acids at Carbon Microfibers: Application to Capillary Electrophoresis - 1995
Bobbitt, D.R., Jackson, W.A. and Hendrickson, H.D., 1995 International Chemical Congress of Pacific Basin Societies, Honolulu, HI, December 17-22, 1995 (INVITED).
Ru(bpy)33+-Based Detection of Amino Acids Separated by Capillary Electrophoresis - 1994
Bobbitt, D.R. and Jackson, W.A., 1994 National American Chemical Society Meeting, San Diego, CA, March 13-17, 1994 (INVITED).
Development and Application of Dynamically Modified, Biospecific Optical Fiber Sensors - 1994
Bobbitt, D.R., Rocky Mountain Section - Society for Applied Spectroscopy, Denver CO, April 20, 1994 (INVITED).
Dynamically Modified Optical Fiber Sensors for Chemical Analysis Under Extreme Measurement Conditions - 1994
Bobbitt, D.R., DOW Chemical, Freeport, TX and Houston Section - Society for Applied Spectroscopy, Houston, TX, April 25-26, 1994 (INVITED).
Novel Protein Sequencing Methodologies Based on Capillary Electrophoretic Separation and Ultra-sensitive Chemiluminescent Detection - 1994
Bobbitt, D.R., IGEN Inc., Rockville, MD, August 1, 1994 (INVITED).
Ru(bpy)33+-Based Detection of Underivatized Amino Acids Separated by Capillary Electrophoresis - 1994
Bobbitt, D.R., Jackson, W.A. and Hendrickson, H., Federation of Analytical Chemistry and Spectroscopy Society Meeting, October 14-19, 1994 (INVITED).
Surface Altered Binding Effects and Their Implications for the Development of Dynamically Modified Optical Fiber Sensors - 1994
Baten, J.M. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Cleveland, OH, October 14-19, 1994.
Development and Application of Polarimetric Methods for Chiral-Selective Analysis - 1994
Lodevico, R. Bobbitt, D.R. and Edkins, T.J., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Cleveland, OH, October 14-19, 1994.
Development and Application of New Techniques for Probing Chiral Species Using Polarized Light - 1994
Ng, K., Bobbitt, D.R. and Edkins, T.J., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Cleveland, OH, October 14-19,1994.
Chromatographic and Laser-based Polarimetric Studies of Pharmacologically Active Materials as a Source of Enhanced Qualitative and Quantitative Information - 1993
Bobbitt, D.R., 24th Ohio Valley Chromatography Symposium, Hueston Woods, OH, June 23-25, 1993 (INVITED).
Development of Polarimetric Methods for Enantiomeric-Selective Analysis - 1993
Lodevico, R.G. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Detroit, MI, October 17-22, 1993.
Ultra-sensitive Measurement of Specific Rotation via Laser-based Polarimetry: Application to the Study of Complex Biomolecular Structure - 1993
Ng, K.W. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Detroit, MI, October 17-22, 1993.
Interaction of Avidin and Hydrophobically Associated Biotin as a Model for a Dynamically Modified Optical Fiber Immuno-Sensor - 1993
Bobbitt, D.R. and Wang, Y., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Detroit, MI, October 17-22, 1993 (INVITED).
Optical Fiber-based Sensor for Calcium Using Hydrophobically Associated Calcein as an Indicator - 1993
Wang, Y. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Detroit, MI, October 17-22, 1993 (INVITED).
In situ Generated Tris(2,2'-bipyridyl) Ruthenium(III) on Glassy Carbon as a Chemiluminescent Reagent for the Detection of Amino Acids and Polypeptide - 1993
Bobbitt, D.R. and Jackson, W.A., Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Detroit, MI, October 17-22, 1993 (INVITED).
Renewable Optical Fiber Sensors Based on a Dynamically Modified Surface Interaction - 1992
Bobbitt, D.R., Wang, Y. and Ogasawara, F.K., SPIE: Progress in Biomedical Optics, Los Angeles, CA, January 23-24, 1992.
Effect of pH, Ionic Strength and Solvent Hydrophobicity on the Luciferase - Catalyzed Bioluminescent Reaction of Long-Chain Aldehydes with Reduced FMN - 1992
Frazier, D. and Bobbitt, D.R., ACS National Meeting, San Francisco, CA, April 5-10, 1992.
Improvements in the Determination of Enantiomeric Purity Through Combined Enantio-selective Separation and Detection Modes - 1992
Bobbitt, D.R., R.W. Johnson Pharmaceutical Research Institute, Spring House, PA, July 14, 1992 (INVITED).
Polarimetric Techniques for Pharmaceutical Analysis - 1992
Bobbitt, D.R., Monsanto Company, St. Louis, MO, August 14, 1992 (INVITED).
Electrochemically Generated Ru(bpy) 3+3 for the Direct Chemiluminescent Detection of Amino Acids - 1992
Bobbitt, D.R. and Jackson, W.A., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Philadelphia, PA, September 20-25, 1992.
Polarization-Selective Spectroscopy: New Techniques for Studying Complex Biomolecular Structure - 1992
Bobbitt, D.R. and Ng, K., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Philadelphia, PA, September 20-25, 1992 (INVITED).
General Method for the Production of Biospecific Optical Fiber Sensors Based on a Dynamically Associated Surface Interaction - 1992
Bobbitt, D.R., Wang, Y., Titus, K.P. and Ogasawara, F.K., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Philadelphia, PA, September 20-25, 1992.
Investigation of the Effect of pH, Ionic Strength and Solvent Polarity on the Chemiluminescent Reaction of Aldehydic Pheromones with Reduced Flavin Mononucleotide - 1992
Bobbitt, D.R., Brune, S.N. and Frazier, D.B., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Philadelphia, PA, September 20-25, 1992.
Enantiomeric Quantitation without Separation of Tramadol Hydrochloride via Laser-Based Polarimetry - 1992
Edkins, T.J., Fronheiser, M., Bobbitt, D.R. and Mills, J.E., Federation of Analytical Chemistry and Spectroscopy Society Meeting, Philadelphia, PA, September 20-25, 1992.
Role of pH, Stoichiometry and Electron Donating/Withdrawing Character on the Chemiluminescent Reaction of Tris(2,2'-bipyridyl)Ruthenium(III) with Amino Acids - 1992
New Approaches to Signal-to-Noise Optimization in Background Limited Photothermal Measurements - 1991
Bobbitt, D.R., SPIE OE/LASE '91, Los Angeles, CA, January 20-25, 1991 (INVITED).
Chemiluminescent Detection of Amino Acids Using Electrogenerated Tris(2,2'-bipyridyl) Ruthenium(III) - 1991
Brune, S.N. and Bobbitt, D.R., ACS National Meeting, Atlanta, GA, April 14-19, 1991.
Bioluminescent Detection of Insect Pheromones Using Flow Injection Analysis" - 1991
Brune, S.N., Phillips, J.R. and Bobbitt, D.R., ACS National Meeting, Atlanta, GA, April 14-19, 1991.
Enantio-Selective Analysis via Laser-Based Polarimetry: Does the Right-Hand Know What the Left-Hand is Doing - 1991
Bobbitt, D.R., R.W. Johnson Pharmaceutical Research Institute, Spring House, PA, August 22, 1991 (INVITED).
Combined Flow Injection Analysis/Bioluminescence Detection System for the Analysis of Insect Pheromones" - 1991
Bobbitt, D.R., Eastern Analytical Symposium, New York, NY, November 10-15, 1991.
Application of Chiral-Selective Detection to the Study of Antibiotic Materials - 1991
Bobbitt, D.R., Eastern Analytical Symposium, New York NY, November 10-15, 1991.
Polarization-Selective Detection of Biomolecules - 1991
Bobbitt, D.R., 14th International Conference on Lasers, San Diego, CA, December 9-13, 1991 (INVITED).
Chemiluminescent Detection of Biomolecules Using Electrogenerated Tris(2,2'-bipyridine) Ruthenium(III) - 1990
Brune, S.N. and Bobbitt, D.R., ACS National Meeting, Boston, MA, April 22-27, 1990.
Development of a Dynamically Modified Optical Fiber Sensor for Riboflavin Binding Protein - 1990
Miller, K.M., Ogasawara, F.K. and Bobbitt, D.R., ACS National Meeting, Boston, MA, April 22 27, 1990.
Performance of Dynamically Modified, Biospecific Optical Fiber Sensors - 1990
Ogasawara, F.K., Miller, K.M. and Bobbitt, D.R., ACS National Meeting, Boston, MA, April 22-27, 1990.
Indirect Photothermal Spectroscopy: Universal Detection in Microcolumn HPLC - 1990
Bobbitt, D.R., Shell Development, Westhollow Research Center, Houston, TX, May 23, 1990 (INVITED).
New Detection Strategies for Amino Acid Analysis - 1990
Bobbitt, D.R., Gordon Research Conference on Analytical Chemistry, New Hampton, NH, August 9, 1990 (INVITED).
Fluorescence and Fluorescence Quenching Assays Via Dynamically Modified Fiber Optic Sensors - 1990
Ogasawara, F.K., Miller, K.M. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies, Cleveland, OH, October 7-12, 1990.
Laser-Based Polarimetric Detection of Gentamicin in Milk - 1990
Rice, P.D., Ng, K., Ogasawara, F.K. and Bobbitt, D.R., Federation of Analytical Chemistry and Spectroscopy Societies, Cleveland, OH, October 7-12, 1990.
Application of Polarimetric Techniques to the Study of Enzyme Kinetics - 1990
Bobbitt, D.R. and Rice, P.D., Federation of Analytical Chemistry and Spectroscopy Societies, Cleveland, OH, October 7-12, 1990 (INVITED).
Direct and Indirect Photothermal Detection in HPLC - 1990
Bobbitt, D.R., Erskine, S.R. and Thorne, J.B., Federation of Analytical Chemistry and Spectroscopy Societies, Cleveland, OH, October 7-12, 1990 (INVITED).
Sensitive Photothermal Measurements under Background-Limited Conditions - 1990
Bobbitt, D.R., 13th International Conference on Lasers, San Diego, CA, December 9-14, 1990 (INVITED).
Development of Photothermally-Detected Time-Resolved CD for the Study of Protein Dynamics
, Bobbitt, D.R., Gordon Research Conference on Analytical Chemistry, New Hampton, NH, August 7, 1990.
Specific Rotation Measurements of Degraded Topiramate Drug Product Using Laser-based Polarimetric HPLC Detection
Edkins, T.J., Newburger, J., Rossi, T.M. and Bobbitt, D.R., Eastern Analytical Symposium, Somerset, NJ, November 1996.
Appointments
Duration
Rank
Department / School
College / Office
University / Company
2008-Present
Provost & V.P. for Academic Affairs
The University of Texas at Arlington
2003-2008
Dean
J. William Fulbright College of Arts and Sciences
University of Arkansas
2001-2008
Campus Director
UAF - Arkansas Biosciences Institute
University of Arkansas
2000-2008
Associate Dean for Research and Sciences and Dean
Fulbright College of Arts and Sciences
University of Arkansas
1993-2008
Professor
Department of Chemistry and Biochemistry
University of Arkansas
2002-2003
Interim Dean
Fulbright College of Arts and Sciences
University of Arkansas
1998-2000
Chair
Department of Chemistry and Biochemistry
University of Arkansas
1992-1998
Vice Chair
Department of Chemistry and Biochemistry
University of Arkansas
1989-1993
Associate Professor
Department of Chemistry and Biochemistry
University of Arkansas
1985-1989
Assistant Professor
Department of Chemistry and Biochemistry
University of Arkansas
1979-1980
Process Control Chemist
E.I. DuPont de Nemours
Synergistic Activities
Journal Reviews
Analytical Chemistry Microchemical Journal Journal of Chromatography Journal of Chromatographic Science Talanta Applied Spectroscopy Analytical Chimica Acta Journal of Chemical Education Chirality Enantiomer Journal of the American Chemical Society
Funding Agency Reviews
Petroleum Research Fund (ACS) National Science Foundation National Institutes of Health Research Corporation
Consultant
Shell Chemical Company (1989) Sanyo Chemical Company (1990) R.W. Johnson Pharmaceutical Research Institute (1991-2000) Monsanto Company (1992) Finnegan, Henderson, Farabow, Garrett & Dunner, patent attorneys (1994-95) IGEN, Inc. (1994-95) PDR-Chiral Inc. (1997-2002) Alcon, Inc. (2000) ViroPharma, Inc. (2001) Virtual Incubation Corporation (2002-) Beta Rubicon Inc. (2002-)
Organized Symposia
"Polarization Selective Techniques in Molecular Spectroscopy", Federation of Analytical Chemistry and Spectroscopy Society Meeting, Chicago IL, 1989. "Lasers in Chemistry", 13th International Conference on Lasers, San Diego CA, Dec. 9-14, 1990. "Laser-Based Analytical Techniques", 14th International Conference on Lasers, San Diego CA, Dec. 9-14, 1991 "Optical-Based Sensors for Biospecific and Chemispecific Analysis", Federation of Analytical Chemistry and Spectroscopy Societies Meeting, Cincinnati OH, October 15-20, 1995. “New Developments in Enantio-Selective Analysis”, ACS National Meeting, San Diego CA, March 2001.
Federal Advisory Panels
1991-1992 Member, National Institutes of Health Review Panel: Biochemical Instrumentation
1992-1993 Member, Pre-doctoral Fellowship Competition Review Panel, National Science Foundation.
1994-2002 Member, National Institutes of Health Review Panel: Bioengineering and Physiology (SSS#8; 3 meetings/year)
1999-2000 Chair, National Institutes of Health Review Panel: Bioengineering and Physiology (SSS#8)
July 2001-Oct. 2001 Chair, National Institutes of Health Review Panel: Bioengineering and Physiology (SSS#8)
April 2002 National Science Foundation Review Panel: Biosensors
May 2002 Department of Energy Review Panel: EMSP Analytical Chemistry.
2005-present National Institutes of Health Study Section: Biomedical Sensing, Measurement and Instrumentation (SSS#10); Chair 2006-07.
Support
Duration
Title
Sponsor
Amount
Status
2006-2010
Studio Concept to Enable, Students to Uncover the Rules of Nature at the Small Scale, Bobbitt, D.R. PI
Howard Hughes Medical Institute
$1,500,000
Current
2006-2009
Arkansas REU Site Project: Motivating Undergraduates toward Careers in Science, Bobbitt, D.R. co-PI
National Science Foundation
$248,100
Current
2005-2010
Arkansas Institutional Network for Biomedical research Excellence (AR-INBRE), Bobbitt, D.R. Co-PI (with L. Cornett and H. Benes, University of Arkansas for Medical Sciences) and Director of Outreach Activities
National Institutes of Health
$2,250,000
Current
2003-2006
Research Experience for Undergraduates Site Project in the Chemical and Biochemical Sciences, Bobbitt, D.R. PI
National Science Foundation
$234,000
Previous
2001-2004
Partnerships for Biomedical Research In Arkansas, Bobbitt, D.R. co-PI (with L. Cornett and H. Benes, University of Arkansas for Medical Sciences)
National Institutes of Health
$9,600,000, $1,640,000-UAF
Previous
2000-2003
Research Experience for Undergraduates Site Project in Chemistry and Biochemistry, Bobbitt, D.R. PI
National Science Foundation
$174,000 (with supplement)
Previous
2000-2002
Development and Application of Polarimetric Methodology for Large-Scale, Enantio-Selective Separations, Bobbitt, D.R. PI
Center for Process Analytical Chemistry – University of Washington and PDR, Inc.
$105,000
Previous
1999-2002
Center for Sensor Technology and Research (CSTAR), Bobbitt, D.R. co-PI
National Science Foundation
$1,000,000
Previous
1998-2001
Equipment Grant, Novel Applications of Polarimetric Instrumentation
PDR-Chiral, Inc.
$105,000
Previous
1998-1999
Development and Application of Novel Ru(bpy)33+ - based Chemiluminescent Labels for Proteins, Jonathan Townley, Undergraduate Research Student
SILO
$3,700
Previous
1997-2000
Research Experience for Undergraduates Site Project in Chemistry and Biochemistry, Bobbitt, D.R. PI
NationBiochemistryal Science Foundation
$157,405
Previous
1997-1998
Development of New Approaches for Chiral-Selective Analysis
Equipment Grant, R.W. Johnson Pharmaceutical Research Institute
$80,000
Previous
1995-1998
Two Year Extension for Special Creativity - REU Site Project in Chemistry and Biochemistry, Bobbitt, D.R., PI
National Science Foundation
$110,000
Previous
1994-1999
Undergraduate and Graduate Education Enhancement and Outreach at the University of Arkansas, Bobbitt, D.R. co-PI
Howard Hughes Medical Institute
$1,337,424
Previous
1993-1995
Combination of Chiral-Selective Separation Modes with Polarization-Selective Detection for the Enhanced Resolution of Enantiomeric Species, Bobbitt, D.R. PI
R.W. Johnson Pharmaceutical Research Institute
$25,000
Previous
1993-1995
Fourier-Transform Infrared Spectroscopy of Surface Bound and Surface Adsorbed Species – purchase of FT-IR Instrumentation, Bobbitt, D.R. co PI (one of three investigators)
National Science Foundation
$85,000
Previous
1992-1995
REU Site Project in Chemistry and Biochemistry, Bobbitt, D.R. PI
National Science Foundation
$152,485
Previous
1992-1993
Enantiomeric Quantitation without Separation
Equipment Grant, R.W. Johnson Pharmaceutical Research Institute
$56,000
Previous
1992-1993
Center for the Study of Protein Dynamics, II, Bobbitt, D.R. (one of ten center investigators)
National Science Foundation
$3,300,000
Previous
1991-1993
Combination of Solvent Gradients with Laser-Based Polarimetry
Equipment Grant, R.W. Johnson Pharmaceutical Research Institute
$50,000
Previous
1990-1994
Protein Dynamics Via Time-Resolved Circular Dichroism, Bobbitt, D.R. PI
National Institutes of Health
$105,000
Previous
1990-1992
Center for the Study of Protein Dynamics, Bobbitt, D.R. co-PI (one of eight center investigators)
National Science Foundation
$1,100,000
Previous
1989-1993
Development of Chemiluminescent Techniques for the Surveillance of Insect Populations, Bobbitt, D.R. Co-PI
U.S. Department of Agriculture
$80,000
Previous
1989-1992
Research Experiences for Undergraduates Site Project in Chemistry, Bobbitt, D.R. PI
National Science Foundation
$115,550
Previous
1988-1995
Teacher-Scholar Fellowship
Camille and Henry Dreyfus Foundation Inc.
$50,000
Previous
1988-1989
Nuclear Processes and Radon Analysis: An Experiment for the Undergraduate Chemistry Curriculum
Department of Energy
$1,284
Previous
1988-1989
Ultra-sensitive Detection of Circular Dichroism via the Differential Thermal Lens Technique
Department of Energy
$2,107
Previous
1988-1989
Experimental Development of the Raman Induced Kerr Effect: A Unique Spectroscopic Technique
Department of Energy
$3,880
Previous
1988-1988
Analytical Division Summer Research Fellowship for Steven R. Erskine
American Chemical Society
$3,000
Previous
1987-1989
New Approaches to the Detection of Circular Dichroism, Bobbitt, D.R. PI
Petroleum Research Fund
$20,500
Previous
1987-1989
Dynamically Modified, Biospecific Optical Fiber Sensors, Bobbitt, D.R. PI
National Institutes of Health
$35,000
Previous
1986-1987
Experimental Development and Application of the Raman Induced Kerr Effect
Department of Energy
$6,400
Previous
1985-1986
Development of a Thermal-Optically Detected Circular Dichroism Spectrometer
Department of Energy
$3,821
Previous
Development and Evaluation of Instrument Simulation Software for Undergraduate Chemistry Laboratories
Educational Development Grant, University of Arkansas
$2,840
Previous
Introduction of Lasers into the Undergraduate Chemistry Curriculum
Teaching Innovation Grant, Fulbright College of Arts and Sciences
$1,000
Previous
Patents
Chemiluminescent Detection of Amino Acids
USPTO Donald R. Bobbitt and Stephen N. Brune; issued March 29, 1994; no. 5,298,427.
2. Sensitive Detection of Underivatized Amines and Amino Acids Using In Situ-Generated Ru(bpy)33+ after Separation by Capillary Electrophoresis
USPTO Donald R. Bobbitt and Warren A. Jackson, issued March 25, 1997; no. 5,614,073.
Additional Information
Awards
1983 Elected Member Phi Kappa Phi National Honor Society
1984-1985 Phillips Petroleum Fellowship in Analytical Chemistry, Iowa State University, Ames, Iowa
1988-1993 Camille and Henry Dreyfus Foundation Teacher-Scholar Fellowship, Camille and Henry Dreyfus Foundation, New York, New York
1991 Fulbright College Master Teacher Award, Fulbright College of Arts and Sciences, University of Arkansas, Fayetteville, Arkansas
1991 University of Arkansas Alumni Association Award in Teaching and Research, University of Arkansas, Fayetteville, Arkansas
1994-1995 National Tour Speaker, Society for Applied Spectroscopy, Fredrick, Maryland
1994-2000 Associate Editor – The Microchemical Journal, Elsevier Science B. V., New York, New York
1996-2001 Editorial Advisory Board – Talanta, Elsevier Science B. V., New York, New York
Boards and Other Service
2004-present Winthrop Rockefeller Institute
2005-present Virtual Incubation Corporation
2005-present North Arkansas Symphony Orchestra
2007-present Walton Arts Center
Graduate Student Training
Y.Y. Shao, M.S. 1988 • Ph.D., Baylor University, 1994 • Staff Position; Cleveland Clinic Research Foundation, Cleveland, OH.
Steven R. Erskine, Ph.D. 1989 • R.W. Rhowden Award -, Research and Service (University of Arkansas); Graduate College Research Award ($8,000); ACS - Analytical Division Summer Fellowship ($3,000);Sigma Xi Research Award • Senior Research Chemist and Group Leader, Dow Chemical Company; Freeport TX.
Faye K. Ogasawara, Ph.D. 1991 • Research Chemist, State of Michigan Environmental Protection Laboratory, Lansing, MI.
John Thorne, M.S. 1991 • Staff Scientist, Environmental Concerns, State College, PA.
Kim P. Titus, M.S. 1992 • Research Assistant, The University of Idaho, Moscow, ID.
P.D. Rice, Ph.D. 1992 • Coblentz Society Award in Vibrational Spectroscopy, 1988-89 • Senior Research Chemist, Seale Inc., Chicago, IL.
Stephen N. Brune, Ph.D. 1992 • Senior Chemist, Pfizer Inc., Groton, CT.
Warren A. Jackson, Ph.D. 1994 • Graduate College Thesis Fellowship, University of Arkansas • Senior Analytical Chemist, Eastman, Inc., Kingsport, TN.
Howard Hendrickson, Ph.D. 1997 • National Institutes of Health Career Development Award (2001-2006). • Research Assistant Professor, University of Arkansas for Medical Sciences, Little Rock, AR.
Paul Anderson, M.S. 1998 • Development Chemist, Femtometrics Corp., Irvine, CA.
Xin Wang, Ph.D. 2000 • Post-doctoral Fellow, Medical College of South Carolina, Charleston, SC.
Darrell R. Fry, Ph.D. 2001 • Assistant Professor, Mississippi State University, Starksville, MS.
Sean Linder, Ph.D. 2001 • Director, Veterinary Toxicology Laboratory, Little Rock, AR
Undergraduate Honors Students
James Claus, B.S.-Suma Cum Laude 1991 • Doctoral study at Massachusetts Institute of Technology • NSF Pre-doctoral Fellowship • Scientist, Zymogenetics, Seattle, WA.
Emily Hopkins, B.S-Cum Laude 1991 • M.D., The University of Arkansas for Medical Sciences • Public Health Service Fellowship
Machele Miller, B.S-Cum Laude 1991 • M.S., The University of Nebraska
Diane Frazier, B.S.-Cum Laude 1992 • 1992 University of Arkansas Undergraduate Research Award for Application ($1000)
Zidia Pittman, B.S. 1996 • Patent Examiner, Washington D.C.
Jonathan Townley, B.S.-Suma Cum Laude 2000 • Medical study, The University of Arkansas for Medical Sciences • SILO Research Fellowship
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Faculty Profile
Arlington, TX 76019 
Mail Box: 19118, 317 Davis Hall 
817-272-2103 
817-272-3400 
