Medical instrumentation and imaging, Minimally invasive and non-invasive spectroscopy and imaging of tissue, Optical diffuse imaging for cancer prognosis and brain activities
Liu, H.; Sharma, V.; Roehrborn, C. G. Apparatus and Methods for Guidance of Prostate Needle Biopsy. Provisional, filed. July, 2009.
Patent
None
Submitted
2009
F. Tian, V. Sharma, F. A. Kozel, and H. Liu. "Functional Near Infrared Spectroscopy to Investigate Hemodynamic Responses to Deception in the Prefrontal Cortex," Brain Research, vol. 1303, pp. 120-130, 2009.
Journal Article
Refereed/Juried
Published
2009
F. Tian, B. Chance, and H. Liu. "Investigation of the Prefrontal Cortex in Response to Duration-Variable Anagram Tasks Using Functional Near Infrared Spectroscopy," J. of Biomed. Opt., vol. 14, no. 5, pp. 054016, 2009.
Journal Article
Refereed/Juried
Published
2009
V. Sharma, D. Kashyap, A. Mathker, S. Narvenkar, K. Bensalah, W. Kabbani, A. Tuncel, J. A. Cadeddu, and H. Liu. "Optical Reflectance Spectroscopy for Detection of Human Prostate Cancer," Proc. of IEEE Engineering in Medicine and Biology, 2009.
Journal Article
Refereed/Juried
Accepted
2009
F. A. Kozel, F. Tian, S. C. Dhamne, P. Croarkin, S. M. McClintock, A. Elliott, K. Mapes, M. M. Husain, and H. Liu. "Using Simultaneous Repetitive Transcranial Magnetic Stimulation/Functional Near Infrared Spectroscopy (rTMS/fNIRS) to Measure Brain Activation and Connectivity," NeuroImage, vol. 47, pp. 456-472, 2009.
Journal Article
Refereed/Juried
Published
Affiliations
University of North Texas Health Science Center
Sept. 2000 – present:
Affiliate Member of the Institute for Cancer Research, The University of North Texas Health Science Center, Fort Worth, TX.
UT Southwestern Medical Center
Sept. 1996 – present:
Adjunct Faculty, Joint Program in Biomedical Engineering, The Univ. of Texas Southwestern Graduate School of Biomedical Sciences, Dallas, TX.
Appointments
Duration
Rank
Department / School
College / Office
University / Company
2006-present
Professor
Bioengineering
College of Engineering
University of Texas at Arlington
2000-present
Affiliate Member
Institute for Cancer Research
University of North Texas Health Science Center
1996-present
Adjunct Faculty
Joint Program in Biomedical Engineering
The University of Texas Southwestern Graduate School of Biomedical Engineering
2001-2006
Associate Professor
Biomedical Engineering
College of Engineering
University of Texas at Arlington
1996-2001
Assistant Professor
Biomedical Engineering
College of Engineering
University of Texas at Arlington
1997-1997
Summer Research Faculty Fellow
Air Force Research Lab, Albuquerque, NM
1994-1996
Research Associate and Post-doctoral fellow
Biochem & Biophysics
School of Medicine
University of Pennsylvania
1994-1996
Post-doctoral Fellow
Department of Biochemistry and Biophyscs
Britton Chance's Laboratory
The University of Pennsylvania
1992-1996
Research Associate
University City Science Center
Institute for Biophysical and Biomedical Research (IBBR)
Philadelphia
1989-1992
Research Assistant
Physics Department
Wake Forest University, NC
1987-1989
Teaching/Research Assistant
Physics Department
Wake Forest University, NC
Synergistic Activities
Collaborators
Collaborators at UTSW (University of Texas Southwestern MedicalCenter at Dallas, TX):
Ralph P. Mason, Professor, Department of Radiology, UTSW;
Cole A. Giller, (1998-2004) Neurosurgeon and Associate Professor, Department of Neurological Surgery, UTSW; (2004-present) Medical Director of Radiosurgery Center at Baylor University Medical Center at Dallas;
Edward Livingston, Professor and Chairman, Department of General Surgery, UTSW;
Jeff Cadeddu, Associate Professor, Department of Urology, UTSW;
Claus G. Roehrborn, MD, Professor and Chair, Department of Urology, UTSW;
Richard Briggs, Professor and Director of Neuroimaging, Department of Radiology, UTSW;
Dwight German (2000-2004), Professor, Department of Psychiatry, UTSW;
Mauricio Delgado, MD, Professor of Neurology, Department of Neurology, UTSW;
Frank Andrew Kozel, MD, Assistant Professor of Psychiatry, UTSW
Mustafa Husain, MD, Professor of Psychiatry and Internal Medicine, UTSW
Collaborators at UTA (University of Texas at Arlington):
Khosrow Behbehani, Professor and Chairman, Department of BioEngineering, UTA;
George Alexandrakis, Assistant Professor, Department of BioEngineering, UTA.
Mario Romero-Ortega, Associate Professor, Department of BioEngineering, UTA
Boping Wang, Professor, Department of Mechanical Engineering, UTA;
Jianzhong Su, Professor, Department of Mathematics, UTA;
Yuan Bo Peng, Assistant Professor, Department of Psychology, UTA.
Hua Shan, Assistant Professor, Department of Mathematics, UTA.
Liping Tang, Professor of Bioengineering, UTA
Seoung Kim, Assistant Professor, Industrial Engineering, UTA
Collaborators at other Universities:
Wei Chen (2003-2005), Professor and Director of Biomedical Engineering Program, Department of Physics and Engineering, University of CentralOklahoma;
Shaohua Yang, Assistant Professor, Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Wroth. TX.
Anna Ratka (2004-2006), Associate Professor, Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Wroth. TX.
Ignacy Gryczynski, Professor and Director, Microscopy Core Facility, Department of Cell Biology and Genetics,UNTHSC.
Zygmunt Gryczynski, Professor, Department of Molecular Biology and Immunology, UNTHSC.
Michael Klibanov, Professor of Mathematics, University of North Carolina at Charlotte, NC
James Simpkins, Professor and Chairman, Department of Pharmacology and Neuroscience, UNTHSC at Fort Worth, TX
Support
Duration
Title
Sponsor
Amount
Status
2009-2012
Development of a Hybrid Optical Biopsy Probe to Improve Prostate Cancer Diagnosis
Department of Defense Prostate Cancer Research Program
Current
2009-2012
Computational Optical Tomography for Anti-stroke Therapy
NINDS/NIH (R33)
Current
2009-2010
Development of a Real-Time, Optically Guided Needle Biopsy System for Improved Prostate Cancer Diagnosis
Texas Ignition Fund from the University of Texas System
Current
2008-2009
Assessment of Neuroplasticity in children with CP: A multi-source-detector near infrared spectroscopy imaging study
United Cerebral Palsy Research & Educational Foundation
Current
2007-2009
Computational Optical Tomography for Anti-stroke Therapy
NINDS/NIH (R21)
Previous
2006-2009
Establishment of a Comprehensive Medical Imaging Center, in joint collaboration with UT Southwestern Medical Center at Dallas and The University of Texas at Dallas
Congressional “Ear Mark” funding
Current
2006-2006
Novel Approach to Measurement of Hot Flashes by Near Infrared Spectroscopy
UTA/UNTHSC research seed funding for collaboration
Previous
2006-2006
Microcirculatory Dysfunction: Potential Therapeutic Target of Estrogen Against Ischemic Stroke
UTA/UNTHSC research seed funding for collaboration
Previous
2005-2006
Inter-disciplinary Laboratory for Diffuse Optical Medical Imaging
The University of Texas System, STARS program for funding equipment
Previous
2004-2008
Simultaneous Monitoring of Vascular Oxygenation and Tissue Oxygen Tension of Breast Tumors under Hyperbaric Oxygen Exposure
Department of Defense Breast Cancer Research Program; Pre-
Previous
2004-2007
Noninvasive Monitoring for Optimization of Therapeutic Drug Delivery by Biodegradable Fiber to Prostate Tumor
Department of Defense Prostate Cancer Research Program
Previous
2003-2008
Hemodynamic Imaging for Brain Tumor Prognosis
NCI/NIH (R21/R33)
Previous
2003-2007
Monitoring of Breast Tumor Response to Local Chemotherapeutic Agent Delivered by Biodegradable Fibers
Department of Defense Breast Cancer Research Program; Pre-
Previous
2001-2004
Assessing Vascular Oxygen Dynamics for Breast Tumor Prognosis: comparison between MR BOLD and Near Infra-Red method
Department of Defense Breast Cancer Research Program
Previous
2000-2004
Non-Invasive Monitoring of Breast Tumor Oxygenation: A Key to Tumor Therapy Planning and Tumor Prognosis
Department of Defense Breast Cancer Research Program
Previous
2000-2004
A Near-Infrared Probe for Localization in DBS (Deep Brain Stimulation)
NIH, RO-1
Previous
1999-2001
In vivo Recording from GFP-labeled Neurons in Freely-behaving Normal and Mutant Mice
Haberecht Wildhare-Idea Research Grant, UTSW
Previous
1999-2001
An Automated Neuro-Probe for Localization in Deep Brain Stimulation
ARRI Research Enhancement Program Grant, UTA
Previous
1998-1999
A Continuous-Wave Approach to 3-D Imaging through Turbid Media with a Single Planar Measurement
AFOSR, Summer Extension Grant
Previous
1997-2001
Development of a brain spectrometer for guiding brain surgery and in-vivo monitoring of cerebral oxygenation
The Whitaker Foundation
Previous
1997-1997
UTA Research Enhancement Program
UTA
Previous
1995-1997
Electro-Optical Scanner for Detection of Brain Inhomogeneities
NIH, SBIR Phase II grant
Previous
1994-1994
Electro-Optical Scanner for Detection of Brain Inhomogeneities
February 2008: College of Engineering Excellence in Research Award (one person per year in the college), University of Texas at Arlington
October 2007: Selected to be an Associate Editor for Optics Express, which is a fast growing peer-reviewed, International Optics Journal, with an impact factor of 3.8 in 2006.
May 2007: Distinguished speaker to deliver the hooding address in Wait Chapel during the hooding ceremony held by the Graduate School of Wake Forest University.
April 2006: Research Excellence Award, University of Texas at Arlington;
Jan.-May, 2006: Recipient, Faculty Development Award from UT Arlington for Sabbatical in Functional Neuro-imaging.
April 2005:Research Excellence Award, University of Texas at Arlington.
Jan. 2005:Recipient, the STARS program from the University of Texas System to receive $500,000 for equipment fund.
Jan. 6-7, 2005: Invited to attend "The Academy of Medicine, Engineering, and Science of Texas,"Omni Mandalay Hotel at Las Colinas, Texas.(two faculty members per university within the UT system were invited.)
2004-present:Listed in MarquisWho's Who in the World, 2005 Edition.
April 2004:University Outstanding Research Achievement Award, UTA.
2003-present:Listed in Marquis Who's Who of American Women.
2002-present:Listed in Marquis Who's Who in America.
October 1999: "Chun-Hui" Travel Fund Award for Outstanding Abroad Chinese Scholars, sponsored by Education Ministry of China.
February 1999: College of Engineering Outstanding Young Faculty Award, UT Arlington;
April 1998: Outstanding Young Scientist Award, Houston Biomedical Engineering Symposium, Houston, TX.
May 1990: Sigma Xi Research Award, WakeForest Chapter, Winston-Salem, NC.
May 1990:Graduate Student Association Award for best M.S. Thesis, WakeForestUniversity
Applied O Applied Optics; Applied Spectroscopy; Biomedical Engineering Online; International Journal of Biomedical Imaging; Journal of Biomedical Optics; Journal of Neural Engineering; Journal of Optical Society of America A: Optics and Image Science;Medical Physics; Optical Engineering; Optics Letters; Physics in Medicine and Biology; Photochemistry and Photobiology;Review of Scientific Instruments; Shock Waves; Optics Express; Neuroimage.
Hanli Liu, “Clinical Applications of Diffuse Optical Tomography: cortical reorganization in children with cerebral palsy and study of connectivity under repetitive transcranial magnetic stimulation,” Department of Physics, University of Pennsylvania, PA, Oct. 14, 2009.
Hanli Liu, invited to give a keynote speech for “Optical Methods as used for Molecular Imaging,”the Xiangshan Science Conferences (the 340th Session: Molecular Imaging and Its Applications), sponsored by the Ministry of Science and Technology of China (MOST), Dec. 18-20, 2008, Beijing, P. R. China.
Hanli Liu, “Ultrafast Gated Optical Imaging to Guide Cancer Surgery and Other Surgical Procedures,” SURGICAL RESEARCH ALLIANCE, Department of Surgery, University of Texas Southwestern MedicalCenter, Sept. 17, 2008.
Hanli Liu, “Diffuse Optical Imaging for Studying Neuro-activities,” National Key Laboratory of Cognitive Neuroscience and Learning, BeijingNormalUniversity, Beijing, August 14, 2008.
Hanli Liu, “Optical Spectroscopy and Diffuse Light Imaging: Applications to Cancer Research and Brain Functions,” Children's Cancer Research Institute, University of TexasHealthScienceCenter, San Antonio, Nov. 5, 2007.
Hanli Liu, “Optical Spectroscopy to detect positive cancer margins during laparoscopic surgery,” 7th UT Southwestern in vivo Cancer Cellular and Molecular Imaging, University of Texas Southwestern Medical Center at Dallas, Dallas, TX Oct. 16, 2007.
Hanli Liu, “Physics and Engineering of Optical Imaging,” Department of Physics, UT Arlington, Nov. 8, 2006.
Hanli Liu, “Recent Development on Novel Applications of Optical Spectroscopy and Imaging,” Beckman Laser Institute, UC Irvine, Irvine, CA, Sept. 14, 2006.
Hanli Liu, “Non Invasive and Minimally Invasive Characterization of Tumor Using Optical Methods,” Texas Cancer Registry, Texas Department of State Health Services, Mini-Educational Regional Conference, Fort Worth, Texas, July 14, 2006.
Hanli Liu, “Non-invasive Optical Brain Imaging,”the Mid-Cities Technical Club and the UTACollege of Engineering, Arlington, TX, June 7, 2006.
Hanli Liu, “Non-invasive Optical Brain Imaging,” Gulf War Neuroimaging meeting, UTSW Medical Center at Dallas, Dallas, TX, June 13, 2006.
Hanli Liu, “Non-invasive Imaging for Cancer Prognosis and Therapy Monitoring for Stroke,” University of North Texas Health Sciences Center at Fort Worth, Fort Worth, TX, March 13, 2006.
Hanli Liu, “Near infrared tomography for cancer prognosis and therapy monitoring,” SPIE Medical Imaging International Conference,San Diego, California, 11 - 16 February 2006.
Hanli Liu, “Near Infrared Spectroscopy for Cancer Prognosis and Monitoring Drug Delivery,” Institute of Biological and Life Sciences, ChinaPharmaceuticalUniversity, Nanjing, China, July 1, 2005.
Hanli Liu, “Applications of Near Infrared Spectroscopy and Imaging in Medicine,” Biomedical Engineering Department, NanjingUniversity of Aeronautics and Astronautics, Nanjing, China, July 4, 2005.
Hanli Liu, “Near Infrared Spectroscopy and Imaging for diagnosis of Alzheimer's disease in vivo,”Department of Psychiatry, University of Texas Southwestern Medical Center, November 15, 2004.
Hanli Liu, “Near Infrared Spectroscopy and Imaging for Cancer Study and Brain Activities,” Department of Mechanical & Aerospace Engineering, UTA, October 29, 2004.
Hanli Liu, “Non-invasive Optical Spectroscopy and Imaging for Brain Function Measurements,” Behavioral and Brain Science, Callier Center for Communication Disorders, The University of Texas at Dallas, October 14, 2004.
Hanli Liu, “Diffusive Optical Imaging: a potential imaging tool for neuro-economics study,” InterDisciplinaryCenter forEconomics Sciences, George Mason University, Washington DC, Sept. 24, 2004.
Hanli Liu, “Light scattering from in vivo brain tissues and spinal cord determined by an NIR probe,” MR Center, Harvard Medical School, Boston, MA, December 19, 2003.
Hanli Liu, “Optical Spectroscopy and Imaging for Tissue Engineering,” Department of Biomedical Engineering, Rice University, Houston, TX, November 18, 2003.
Hanli Liu, “Near Infrared Spectroscopy and Imaging for Tumor Prognosis and Therapy Monitoring,” 4th Annual Symposium, Southwestern in vivo Cancer Cellular and Molecular Imaging Program, Dallas, Texas, November 17, 2003.
Hanli Liu, “The Physics of Biomedical Optical Imaging,” Department of Physics, WakeForestUniversity, Winston-Salem, NC, October 9, 2003.
Hanli Liu, “Optical Spectroscopy and Imaging for Neuroscience Applications,” Department of Pharmacology and Neuroscience, University of North Texas Health Sciences Center at Fort Worth, Fort Worth, TX, September 16, 2003.
Hanli Liu, “Optical Spectroscopy and Imaging for Tumor Oximetry and Assisting Neurosurgery in vivo,” National CLEO/QELS Annual Conference, BaltimoreConvention Center, Baltimore, Maryland, June 3-4, 2003.
Hanli Liu, “Light scattering from living brain tissues and spinal cord measured in vivo by a needle NIR probe,” Department of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA, April 18, 2003.
Hanli Liu, “Optical Imaging/Sensing with Near Infrared Light: from organ functions to cellular structures.” Department of Biomedical Engineering, TexasA&MUniversity, College Station, Texas, March 25, 2003.
Hanli Liu, “Phantom and Computer Simulation for Tumor Hemodynamic Study,” Department of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA, Nov. 18, 2002.
Hanli Liu, “Near-Infrared Spectroscopy Used in vivo for Assisting Neurosurgery and Tumor Oximetry,” Progress In Electromagnetics Research Symposium (PIERS) 2002, Cambridge, Massachusetts, July 1-5, 2002.
Hanli Liu "Optical Imaging/Sensing with Near Infrared Light: from organ functions to cellular structures" as a keynote speaker at the 7th Annual Biology-Chemistry Graduate Research Symposium of the University of Texas at Dallas, March 27, 2002.
Hanli Liu and Charles L. Matson, “3-D Localization and Characterization of Breast Tumors Using Diffraction Tomography,” International Symposia on Industrial Lasers and Biomedical Optics IL'99 and BiOS'99, Wuhan, China, October 25-27, 1999.
Hanli Liu, “Near Infrared Spectroscopy used in vivo for Assisting Neurosurgery and Tumor Oximetry,” International Symposia on Industrial Lasers and Biomedical Optics IL'99 andBiOS'99, Wuhan, China, October 25-27, 1999.
Charles L. Matson and Hanli Liu, “Resolution Issues in Optical Diffusion Tomography,” Light for Life, ICO Satellite Conference, Cancún, México, July 28-30, 1999.
Charles L. Matson and Hanli Liu, “Diffraction Tomography in Turbid Media: Theory and Applications,” OSA Annual National Conference, Baltimore, MD, October 1998.
Hanli Liu, “Biomedical Optics Research at UTA,” 16th Annual Houston Conference on Biomedical Engineering Research, Univ. of Houston, Houston, TX, April 1998.
Hanli Liu, “Near Infrared Technology and Current Biomedical Optics at UTA,” Radiology Department of Univ. of Texas Southwestern MedicalSchool, Dallas, TX, April 1998.
Hanli Liu, “Physics and Engineering in Near Infrared Spectroscopy and Imaging of Tissue,” Physics Dept., Wake Forest University, North Carolina, Nov. 1997.
Hanli Liu, “Theory and Applications of Near Infrared Technologies,” Biomedical Engineering Program, Univ. of Texas at Austin, Austin, TX, Nov. 1996.
Hanli Liu, “Near Infrared Spectroscopy and Imaging of Tissue,” at Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, Dallas, TX, Oct. 1996.
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Faculty Profile
501 West 1st Street, Arlington, TX 76019 
Mail Box: 19138, Engineering Lab Building, Room No.: 229 
817-272-2054 
817-272-2251 
