Implanted medical devices are of increasing importance in the practice of medicine. Despite the inert and non-toxic nature of most biomaterials, adverse responses such as device-mediated inflammation, fibrosis, coagulation, and infection are frequent and sometimes life threatening. Unfortunately, the mechanisms underlying these responses are mostly unknown and the lack of such knowledge hinders the development of materials with desired tissue reactivity and compatibility.
Nguyen, K.; Shukla, K. P.; Moctezuma, M.; Braden, A. R. C.; Zhou, J.; Hu, Z.; Tang, L. In vitro studies of the cellular uptake of hydrogel nano- and micro- particles by phagocytes, vascular endothelial and smooth muscle cells. Journal of Biomedical Materials Research2009, 88 (4), 1022-30.
Journal Article
Refereed/Juried
Published
2009
Yang, J.; Gautam, S.; Zhang, Y.; Liu, L.; Dey, J.; Chen, W.; Mason, R. P.; Tang, L. Development of non-phenyl containing biodegradable photoluminescent polymers. Proceeding of National Academy of Science2009, 106 (25), 10086-10091.
Journal Article
Refereed/Juried
Published
2009
Nair, A.; Thevenot, P.; Dey, J.; M-W, Y. J.; Tang, L. Novel polymeric scaffold using protein microbubbles as porogen and growth factor carriers. Tissue Engineering2009, in press.
Journal Article
Refereed/Juried
Accepted
2008
Nair, A.; Thevenot, P.; Hu, W.; Tang, L. Nanotechnology in the treatment and detection of intraocular cancers. Journal of Biomedical Nanotechnology2008, 4, 410-418.
Journal Article
Refereed/Juried
Published
2008
Su, J., Gonzales, H. P., & Tang, L. (2008). Modeling of foreign body reactions to neural implants. In Rubin Wang, Fanji Gu, Enhua Shen. (Eds.), Advances in Cognitive Neurodynamics ICCN 2007: Proceeding of the International Conference on Cognitive Neurodynamic (pp. 879-882). Spring Science+ Business Media BV.
Conference Proceeding
Refereed/Juried
Published
Presentations and Projects
Invited Seminars and Lectures
2000,January, Presentation title: “Molecular mechanisms of biomaterial-mediated tissue responses.”, Children Hospital Oakland Research Institute, Oakland, California.
2000, March, Presentation title: “Phagocyte: surface interaction.”. Pittsburgh Conference. “In vivo sampling. Biocompatibility issues” section, New Orleans, Louisiana.
2000, April, Presentation title: “Foreign body reaction and device-centered infection.”, Center of Immunology and Microbiology,Albany Medical College, Albany, New York.
2000,October, Presentation title: “Artificial Blood.”, Biomedical Engineering program. University of Texas at Arlington, Arlington, Texas.
2001, March 2, Presentation title: “Albumin-affinity coating for improving biocompatibility.”, Department of Materials Science and Engineering, University of Texas at Arlington, Arlington, Texas.
2001,August 14, Presentation title: “Molecular mechanisms of inflammatory responses to peritoneal implants.”, Infimed Therapeutics, Inc., Cambridge, Massachusetts.
2001, December 10, Presentation title: “Inflammatory and fibrotic reactions to implanted biomaterials: mechanisms and implications.”, Pathology Department, University of Linkoping, Linkoping, Sweden.
2002, February 1, Presentation title: “Biocompatibility and sensibility of implantable sensor.”, Automation and Robotics Research Institute, University of Texas at Arlington, Fort Worth, TX.
2002,August 24, Presentation title: “Dog skin plasters and drug controlled deliver devices.”, Convention for Chinese Institute of Engineers (CIE/USA), Dallas, TX.
2003,May 27, Presentation title: “The molecular mechanism of foreign body reactions: The implications to sensor development.”, Molecular Design of Chemical Systems (MODECS) meeting, Novo Nordisk, Hilleroed, Denmark.
2003,July 21, Presentation title: “Biomaterial-mediated inflammation and device-centered infection: Is there a connection?”, Gordon Research Conference, Biomaterials: Biocompatibility/Tissue Engineering. HoldernessSchool, Polymouth, New Hampshire.
2003,August 28, Presentation title: “Foreign body reactions - Natural responses to unnature materials. “, 2003University of Washington Engineered Biomaterials (UWEB) Summer Scientific Symposium, Seattle, Washington.
2004,February 5, Presentation title: “Foreign body reactions and stem cell recruitment �" Is there any connection?”, University of Louisville, Brown CancerCenter, Louisville, Kentucky.
2004,April 16, Presentation title” Novel inflammation-recruited pluripotent stem cells.”, Texas Back Institute, Plano, Texas.
2004,April 16, Presentation title: “UTA capabilities and facilities for industrial joint ventures.”, Alcon Laboratories, Inc., Fort Worth, Texas.
2004, May 11, Presentation title: “Novel peritoneal stem cells.”, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
2005,May 27, Presentation title: “Engineered biomaterials for tissue engineering and stem cell therapies.“, Department of Biology, National Changhua University of Education, Changhua, Taiwan.
2005,August 20, Presentation title: “The current status and future promise of adult stem cell therapies. “, Convention for Chinese Institute of Engineers (CIE/USA), Dallas, Texas.
2005,October 6, Presentation title: “Development of drug delivery nanoparticles.”, Department of Cell Biology and Genetics, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas.
2005,November 1, Presentation title: “Stem cell therapy: promise and problems.”, Master of Arts in interdisciplinary Science program, University of Texas at Arlington, Arlington, Texas.
2005,December 9, Presentation title: “Molecular mechanisms of foreign body reactions.”, UMKC-CRISP seminar, University of Missouri at Kansas City, Kansas City, Missouri.
2006,February 2, Presentation title: “Development of tissue-targeted nanoparticles for treatment of eye diseases.”, JSPS Symposium on Nanoscale Materials for optoelectronics and biotechnology at University of North Texas, Denton, Texas.
2006,April 10, Presentation title: “Nanoparticles for drug delivery.”, BioNano meeting atUniversity of Texas at Dallas, Dallas, Texas.
2006,July 12, Presentation title: “Controlled drug delivery: promise and problems.”, Mid-Cities Technical Club of Arlington monthly seminar, Arlington, Texas.
2006,December 13, Presentation title: “Mechanism-based approaches for altering fibrotic tissue responses to peritoneal implants”, Boston Scientific In., Urology Division, Boston, Massachusetts.
2007,December 13, Presentation title: “Stem cells: aging: osteoporosis”, University of Louisville, Molecular Targets group, Brown Cancer Center, Louisville, Kentucky.
2008,January 30, Presentation title: “Potential role of inflammation on cancer cell metastasis”, University of North Texas Health Science Center, Institute for Cancer & Blood Disorder, Fort Worth, Texas.
2008,February 20, Presentation title: “Biomaterial-mediated inflammation and device-centered infection: Is there a connection?”, University of Texas Southwest Medical Center, Surgery Research Conference, Dallas, Texas.
2008,April 9, Presentation title: “Hyaluronic acid nanoparticles for retinal drug delivery”, Drug Delivery group meeting, Alcon Laboratories, Inc., Fort Worth, Texas.
2009,March 4, Presentation title: “Potential role of inflammatory cytokines and T lymphocytes on cancer cell metastasis”, University of North Texas Health Science Center, Institute for Cancer Grand Round, Fort Worth, Texas.
2009,September 18, Presentation title: “Novel in situ stem cell tissue engineering �"Turing old foes into new friends”, University of Texas at Arlington and University of Texas Southwest Medical Center at Dallas, Bioengineering Videoconference Seminar,Arlington, Texas.
2009,October 7, Presentation title: “Emerging trends of nanotechnology in biomedical research”, University of Texas at Arlington, Physics Department Colloquium, Arlington, Texas.
Affiliations
Member
American Association for The Advance of Science
American Heart Association
Chinese Institute of Engineering
Controlled Release Society
Society for Biomaterials
Society of Chinese Bioscientists in America
Society of Toxicology
The Association for Research in Vision and Ophthalmology
Appointments
Duration
Rank
Department / School
College / Office
University / Company
Present
Professor
Bioengineering
College of Engineering
University of Texas at Arlington
2000-2007
Associate Professor
Bioengineering
College of Engineering
University of Texas at Arlington
1996-2000
Assistant Professor
Pediatrics
Medical College
Baylor College of Medicine
1995-1995
Assistant Professor
Pathology
Medical College
Albany Medical College
Synergistic Activities
Hornor and Award
2001, Young Investigator Award from the Society for Biomaterials.
2002, August, Invited plenary speaker, Biotechnology section, Annual meeting of Chinese Institute of Engineering /USA, Dallas/Forth Worth Chapter.
2002, Visitor Professorship, the Center of Biointerface at University of Uppsala, Uppsala, Sweden.
2003, October, ad hoc study section member, Surgery and Bioengineering study section, National Institute of Health.
2003 April, regular study section member, Biotechnology and Bioengineering study section, National American Heart Association.
2004June, ad hoc study section member, Biomaterials and Bio-interface study section, National Institute of Health.
2004 August, ad hoc study section member, Innate Immunity and Inflammation study section, National Institute of Health.
2004 April and October, regular study section member, Biotechnology and Bioengineering study section, National American Heart Association.
2005 Research Excellent Award in the College of Engineering, University of Texas at Arlington. Arlington, Texas.
2005 February, June, October, ad hoc study section member, Biomaterials and Bio-interface study section, National Institute of Health.
2005 November, ad hoc study section member, Innate Immunity and Inflammation study section, National Institute of Health.
2005 April, regular study section member, Biotechnology and Bioengineering study section, National American Heart Association.
2005 August, Invited plenary speaker, Biotechnology section, Annual Meeting of Chinese Institute of Engineering /USA, Dallas/Forth Worth Chapter.
2006 April, Regular study section member, Western 1B, Lung, Respiration, Resuscitation, Immunology& Microbiology, Surgery, American Heart Association.
2006 February, June, ad hoc study section member, Biomaterials and Bio-interface study section, National Institute of Health.
2006 Research Excellent Award in the College of Engineering, University of Texas at Arlington. Arlington, Texas.
2007 April, regular study section member, Biotechnology and Bioengineering 3 study section, National American Heart Association.
2007 May, ad hoc study section member, Tobacco-Related Disease Research Program, University of California.
2007 Research Excellent Award in the College of Engineering, University of Texas at Arlington. Arlington, Texas.
2007 October, study section member, Nanotechnology Study section, National Institute of Health.
2008 January, September, study section member, Nanotechnology Study section, National Institute of Health.
2008 April, regular study section member, Biotechnology and Bioengineering 1 study section, National American Heart Association.
2008 July, October, study section member, Biomedical Information Science and Technology Initiative (BISTI)-related Small Business Innovative Research study section
2008 Faculty Development Leave Award, University of Texas at Arlington.
2008 Research Excellent Award in the College of Engineering, University of Texas at Arlington, Arlington, Texas.
2008 September, ad hoc study section member, Biomaterials and Bio-interface study section, National Institute of Health.
2008 September, ad hoc study section member, Biomaterials for Tissue Engineering and Gene Delivery, National Institute of Health.
2009 January, study section member, Nanotechnology Study section, National Institute of Health.
2009Phi Kappa Phi Recognized Professor, Chapter of The Honor Society of Phi Kappa Phi, University of Texas at Arlington, Arlington, Texas
2009 June, October, study section member, Biomedical Information Science and Technology Initiative (BISTI)-related Small Business Innovative Research study section
2009 Research Excellent Award in the College of Engineering, University of Texas at Arlington, Arlington, Texas.
Patents and patent applications
Zhibing Hu, Xiaohu Xia, Liping Tang. “Process for synthesis of oil and surfactant-free hyaluronic acid nanoparticles and microparticles”. US Patent #7601704. October 13th, 2009
Tang L, Hansen R III. ”Stem cells for clinical and commercial uses”, sponsored by University of Texas at Arlington, submitted on June, 2003 (USA) and June 2005 (European, Canada, Japan, China).
Tang L. “Nanocoating for improving biocompatibility of medical devices”, sponsored by University of Texas at Arlington, submitted on July, 2004 (USA) and February 2007 (European, Canada, Japan, China; PCT/US2005/013380).
Tang L. “Novel approach for inactivating protein and micro-organisms”, sponsored by University of Texas at Arlington, Submitted on February, 2005.
Tang L. “Tissue engineering methods and compositions”, sponsored by University of Texas at Arlington, Submitted on January, 2007.
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Faculty Profile
Arlington, TX 76019 
Mail Box: 19138 
817.272.6075 
817-272-2251 
