Skip to content. Skip to main navigation.


IACUC Review Procedures

Initial Review of Animal Research

Faculty, staff and students wishing to use animal subjects must first obtain approval from the Institutional Animal Care and Use Committee (IACUC). The first step in the process is to submit a Protocol Application for Use of Vertebrate Animals to the IACUC through the Office of Research Administration:

•  E-mail to or   

• Fax to 817-272-4732

• Drop off at 202 E. Border St., Suite 300

•  Mail to Box 19188                                        

Please NOTE that for Field Research, use this form for protocol application.

The second step is to complete the online animal care training and complete immunization requirements.

Once Research Administration receives the protocol, it will be scheduled for review at the next full board IACUC meeting [see IACUC Meeting schedule]. When reviewing an animal protocol, the IACUC considers the rationale and purpose of the proposed use of animals; justification of the species and number of animals requested; availability of less-invasive procedures and other species; safety of the working environment for personnel involved in the activity; adequacy of training and experience of personnel in the procedures to be used with the animals; appropriate sedation, analgesia, anesthesia, euthanasia, and surgical procedures; and, the unnecessary duplication of experiments.

The Principal Investigator or a representative of the research should attend the meeting to address any concerns or questions of the IACUC. If the PI or representative fails to attend, this can result in the protocol being tabled until the next scheduled IACUC meeting. Once the review is complete the researcher will be notified in writing by the committee Chair of the IACUC’s decision.

Annual Review of Approved Animal Research

In accordance with the USDA Animal Welfare Regulations and UTA IACUC Policy, the IACUC will review approved animal protocols on an annual basis.  An annual review must be completed by the anniversary of the original approval date of a protocol.  To allow ample time for processing and IACUC review, the IACUC requests that Annual Reports be submitted at least 7 days in advance of the anniversary (annual review) date of the protocol.  For example, if the original approval date of a protocol is February 1, 2008, the annual review date is February 1, 2009; however, the Annual Report should be submitted at least 7 days in advance by January 26, 2009.  Research Administration will continue to send reminders via e-mail, including the requested date of submission.  Failure to submit an annual report in a timely manner will result in expiration of the protocol.  If expiration of approval occurs, all activities involving the use of animals must cease immediately.  The research will not be allowed to commence until a new protocol has been submitted, reviewed, and approved by the IACUC.  If a protocol has expired and the use of animals continues, this is considered to be a violation of federal regulations that govern the use of animals in research.

Triennial Review of Approved Animal Research

On the third year of protocol approval, the IACUC requires full review of the protocol at a scheduled, fully convened meeting.  The PI is requested to submit a Triennial Report ensuring that all animal use procedures, personnel, and training is current and updated.  To ensure that the triennial review is completed before the anniversary of the original approval date of the protocol, the PI is required to submit the Triennial Report with sufficient time allowable to complete this process.  The IACUC will perform a full review of the Report as outlined in the section above for review of new protocol applications.  The PI will be notified in writing of IACUC approval.

Review of Amendments/Changes to Approved Animal Research

The IACUC must review any modifications to approved animal research.  The Principal Investigator is responsible for notifying the IACUC of any proposed major changes in approved animal studies, before initiation.  For example, the PI shall submit an Amendment Form for IACUC review before implementation of any of the following:
  1. A change in project title.
  2. A change of funding agency.
  3. A change of number of animals (request for additional animals).
  4. A change or addition of procedures.
  5. A change or addition of animal species.

The PI may request to add or remove personnel by sending an email to or Approval will be granted administratively once all immunization and training requirements have been met.

For more information, please also see UTA's Handbook of IACUC Policies and Procedures.