Technology Development for High-Throughput Structural Biology Research (P01)

Application Due Date: 2013-05-07  |  Post Date: 2010-01-04  |  Funding Number: PAR-10-074

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Description: Purpose. This FOA issued by the National Institute of General Medical Sciences (NIGMS), National Institutes of Health, encourages grant applications from institutions/organizations that propose to develop novel technologies and methodologies underpinning high-throughput structural biology. Applications for new ideas and approaches for protein production and structure determination for classes of challenging proteins are appropriate. Projects related to high-throughput structure determination by X-ray crystallography and NMR, as well as projects addressing other constituent tasks of structural biology, including structural genomics, are relevant to this FOA. Applications should focus on methods development to solve challenging proteins that are not currently amenable to high-throughput structural biology. These challenging proteins include, but are not limited to, membrane proteins, small protein complexes, and proteins from human and other higher eukaryotes. Mechanism of Support. This FOA will utilize the P01 research grant mechanism and runs in parallel with an FOA of identical scientific scope, PAR-10-073, that encourages applications under the R01 mechanism. The program project grant mechanism is designed to support research in which the funding of several interdependent projects as a group offers significant scientific advantages over support of these same projects as individual regular research grants. Funds Available and Anticipated Number of Awards. The total amount to be awarded depends on the scientific merit of applications and the funds available in NIGMSs general funding pool. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the numbers, quality, duration, and costs of the applications.

Expected Number of Awards: Not Available
Estimated Total Program Funding: Not Available
Award Ceiling: None
Award Floor: None
Cost Sharing or Matching Requirement: N
CFDA Number: 93.859
Funding Instrument Type: G

Eligible Applicants:
State Governments
County Governments
City or Township Governments
Special district Governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally r
Nonprofits having a 501(c)(3) status with the IRS, other tha
Nonprofits that do not have a 501(c)(3) status with the IRS,
Private institutions of higher education
For profit organizations other than small businesses
Small businesses