NINDS Exploratory/Developmental Projects in Translational Research for Resistant Epilepsy and Epileptogenesis (R21)

Application Due Date: 2013-05-07  |  Post Date: 2010-03-19  |  Funding Number: PAR-10-143


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Link to Full Announcement: http://grants.nih.gov/grants/guide/pa-files/PAR-10-143.html

Description: Purpose. This funding opportunity announcement (FOA), from the National Institute of Neurological Disorders and Stroke (NINDS) encourages applications for projects intended to complete preliminary steps in the pipeline for the preclinical development of therapeutics to cure epilepsy, prevent the emergence of epilepsy following brain injury (including status epilepticus, traumatic brain injury, stroke, encephalitis, or other injury) or in other high-risk groups, or to better treat individuals with intractable epilepsy. Such projects, if successful, should lead directly to a subsequent project that will include all remaining activities for submission of an Investigational New Drug (IND) or Investigational Device Exemptions (IDE) application to the Food and Drug Administration (FDA). Only Aims required for therapy development can be supported in this program. This program excludes clinical research, basic research, and studies of disease mechanisms. Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) award mechanism and runs in parallel with a FOA of identical scientific scope, PAR-10-144, that encourages applications under the Cooperative Agreement (U01) mechanism. Funds Available and Anticipated Number of Awards. The NINDS funding plan for this FOA will support up to $900,000 total costs, which is sufficient for at least one new application per year for 3 years. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.

Expected Number of Awards: Not Available
Estimated Total Program Funding: Not Available
Award Ceiling: 200000
Award Floor: None
Cost Sharing or Matching Requirement: N
CFDA Number: 93.853
Funding Instrument Type: G

Eligible Applicants:
State Governments
County Governments
City or Township Governments
Special district Governments
Independent school districts
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally r
Nonprofits having a 501(c)(3) status with the IRS, other tha
Nonprofits that do not have a 501(c)(3) status with the IRS,
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others