Since general HPLC analysis is insufficient with respect to qualitative capabilities, risks related to overlooking impurities that can obscure peaks remain. Mass spectrometers are effective at minimizing these risks. With its array of ultrafast capabilities, the single quadrupole LCMS-2020 mass spectrometer provides the ultimate in high-speed analysis with unrivaled sensitivity. It offers quicker and more accurate detection of trace impurities present in pharmaceuticals, environmental pollutants, and other contaminants. And, when combined with a Nexera UHPLC or Prominence ultra-fast LC (UFLC/UFLCXR), you’ll achieve the ultimate in separation performance and productivity.
The ultra-high-speed LCMS-2020 improves the speed and reliability of HPLC/UHPLC analysis, offering dramatic improvements in lab productivity.
To detect both positive ions and negative ions, measurements are performed while switching alternately between positive and negative ionization modes. With the LCMS-2020, ultra high-speed polarity switching is achieved by adopting a high voltage power source loaded with groundbreaking technology (patent pending).
In MS scanning, a range of mass to charge ratios are determined in successive 0.1 m/z steps. This is controlled by applying a rapidly changing voltage to the quadrupole (quadrupole rods). By adopting new technology (patent pending), high ion transmission is achieved without sacrificing sensitivity or resolution, even during high-speed scans up to 15,000 u/sec. Very narrow UFLC peaks can now be properly detected in scan mode acquisition.
Superior sensitivity, repeatability, and linearity are achieved, thanks to the newly developed Qarray® optics.