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Biomedical Technologies

Current Biomedical Technology Research

 In-Vivo Muscle Regeneration 

Muscle RegenerationThis project explores the possibility of regenerating functional muscles in vivo by utilizing the body’s vascular network combined with a miniature bioreactor containing decellularized scaffolds, engineered extracellular matrix (ECM), and stem cells. In collaboration with Dr. Robert Galiano, MD at the Feinberg School of Medicine at Northwestern University, the effort seeks to address current surgical techniques, which have difficulty treating functional muscle-related deficits of the face and extremities that result from burn or blast injuries. UTA is a sub award from Northwestern University.

Funding Agency: Armed Forces Institute of Regenerative Medicine (AFIRM)

  

Biodome

The Biodome stimulates individual tissue types to induce dormant human regenerative pathways which could enable finger regeneration. The miniaturized bioreactor protects and controls the wound environment by sensing environmental factors and modulating biophysical and biochemical cues to maintain ideal conditions for tissue healing. Research is carried out in association with Dr. Stephen Badylak, MD at the McGowan Institute for Regenerative Medicine at the University of Pittsburgh. UTA is a sub award from the University of Pittsburgh.

Funding Agency: Armed Forces Institute of Regenerative Medicine (AFIRM)

 

Bubble Actuator Arrays for Dynamic Surface Control

Bubble ActuatorThe Bubble Actuator Array couples actuation and sensing technologies, and enables dynamic modulation of surface profiles. If applied to an interface, this technology can be used to control and modulate interface pressure. With individual control of each bubble actuator, localized pressure controllability can be achieved, allowing this platform to evolve into many assistive and preventative applications. This effort is currently internally funded.

 

Bubble Actuator Simulation

This work combines numerical analysis, fabrication, and testing of novel interconnected bubble arrays to find solutions to reduce the impact of blast-waves and low-to-moderate speed impacts. Researchers are looking at the mechanics and dynamics associated with a fluid-filled interconnected bubble actuator array under impact conditions. This is an internally funded project carried out by Dr. Bo Yang and Dr. Brian Dennis from the Mechanical and Aerospace Engineering Department.

 

A Smart Sensing and Adaptive Interface for Prosthetics to Improve Fit and Comfort

Smart FitThis project, a collaborative effort with Dr. Haiying Huang in the Mechanical and Aerospace Engineering Department at UTA and Dr. Fan Gao at UTSW Medical Center, is focused on enhancing the long-term socket performance/fit of prosthetics through a smart sensing, adaptive interface, and shear-based dynamic fitting strategy. The effort seeks to provide a major enhancement to the comfort level of the prosthetic and improve quality of life for prosthetic wearers.

Funding Agency: DoD, Congressionally Directed Medical Research Program (CDMRP)

 

Neural Interface Electrodes for Nerve Signal Recording and Stimulation

UTARI researchers are working with Dr. Mario Romero-Ortega of UTD and Dr. Young-tae Kim in the Bioengineering Department at UTA on the development of electrode interfaces that can be utilized in many different biomedical applications with benefits in areas such as neural prosthetics and bioelectronics medicine. This research aims to investigate the use of the new neural interface electrode in stimulating nerves and recording their responses for various treatment and prosthetic applications. This effort is currently internally funded.