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College of Nursing and Health Innovation | The University of Texas at ArlingtonCollege of Nursing and Health Innovation | The University of Texas at Arlington


Touching Lives. Transforming Health Care.

The Marco Brotto Laboratory

Why We Research

In 2012, the Burden of Disease of Report by the WHO revealed that 1.7 billion humans suffer from musculoskeletal (MSK) diseases. One in three older adults falls every years in the United States alone. The cost of treating osteoporosis and sarcopenia in the US is nearing $1 trillion per year, and the health and social consequences are astounding. Therefore, our goal is to combine state-of-the-art complementary approaches ranging from basic to translational and clinical to contribute new mechanistic insights into MSK diseases, and to devise new strategies to to diagnose and treat these devastating conditions.

What We Research

  • Skeletal Muscle Excitation Contraction Coupling Mechanisms
  • Cellular and Molecular Mechanisms of Sarcopenia/Muscle Diseases
  • Bone-Muscle Biochemical Crosstalk
  • Biomarkers for the Risk of Falls and detection of Muscle Weakness in Older Adults
  • Development of Biomedical and Wearable Devices
  • Animal models of Musculoskeletal Research

Who We Are

Dr. Marco BrottoMarco Brotto, BSN, MS, PhD
Lab Director
Dr. Brotto at PubMed

Dr. Leticia BrottoLeticia Brotto, MD
Lab Manager

Dr. Jian HuangJian Huang, PhD
Research Faculty

Dr. Chenglin MoChenglin Mo, PhD
Research Faculty

Dr. Zhiying WangZhiying "Carol" Wang, PhD
Research Faculty

Donnalee PollackDonnalee Pollack
PhD Nursing Student
2018 Jonas Scholar

Partners and Acknowledgements

Partnering Labs and Centers

Founding Member of the Bone-Muscle Research Center at UTA


Research in this lab is funded and supported in part by grants from the National Institutes of Health.

We gratefully acknowledge the generosity of Ms. Peggy Terrell and her support of the George and Mary Hazel Jay Endowment.