The Marco Brotto Laboratory
Why We Research
In 2012, the Burden of Disease of Report by the WHO revealed that 1.7 billion humans suffer from musculoskeletal (MSK) diseases. One in three older adults falls every years in the United States alone. The cost of treating osteoporosis and sarcopenia in the US is nearing $1 trillion per year, and the health and social consequences are astounding. Therefore, our goal is to combine state-of-the-art complementary approaches ranging from basic to translational and clinical to contribute new mechanistic insights into MSK diseases, and to devise new strategies to to diagnose and treat these devastating conditions.
What We Research
- Skeletal Muscle Excitation Contraction Coupling Mechanisms
- Cellular and Molecular Mechanisms of Sarcopenia/Muscle Diseases
- Bone-Muscle Biochemical Crosstalk
- Biomarkers for the Risk of Falls and detection of Muscle Weakness in Older Adults
- Development of Biomedical and Wearable Devices
- Animal models of Musculoskeletal Research
Who We Are
Marco Brotto, BSN, MS, PhD
Dr. Brotto at PubMed
Leticia Brotto, MD
Jian Huang, PhD
Chenglin Mo, PhD
Zhiying "Carol" Wang, PhD
PhD Nursing Student
2018 Jonas Scholar
Partners and Acknowledgements
Partnering Labs and Centers
Research in this lab is funded and supported in part by grants from the National Institutes of Health.
We gratefully acknowledge the generosity of Ms. Peggy Terrell and her support of the George and Mary Hazel Jay Endowment.