Hevener, K., Yun, M.K., Qi, J., Kerr, I., Babaoglu, K., Hurdle, J., Balakrishna, K., White, S. and Lee, R. (2010) Structural studies of pterin-based inhibitors of dihydropteroate synthase. J. Med. Chem.;53:166-77.
Budha, N.R., Lee, R., Hurdle, J.G., Lee, R.E. and Meibohm, B. (2009) Simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacterium tuberculosis. Tuberculosis (Edinb); 89:378-85.
Hurdle, J.G*., Yendapally, R., Sun D and Lee, R.E. (2009) Evaluation of analogs of reutericyclin as prospective candidates for staphylococcal skin infections. Antimicrob. Agents Chemother. 53:4028-31. *Communicating author.
Sun, D., Scherman, M. S., Jones, V., Hurdle, J.G., Lenaerts, A. J., McNeill, M. R. and Lee, R.E. Discovery, synthesis and biological evaluation of piperidinol analogs with anti-tuberculosis activity. Bioorg. Med. Chem. 17:3588-3599
Grimes, K. D., Lu, Y., Zhang, Y., Luna, V. A., Hurdle, J. G., Carson, E. I., Qi, J., Kudrimoti, S., Rock, C. O., and Lee, R.E. (2008) Novel acylphosphate mimetics that target PlsY, an essential acyltransferase in Gram-positive bacteria. Chem. Med. Chem. 3:1936-1945.
Hurdle, J.G., Lee, R.B, Budha, N. Carson, E.I., Qi, J., Scherman, M.S., Cho, S.H., McNeil, M.R., Lenaerts, A.J., Franzblau, S.G, Meibohm, B., Lee, R.E. A microbiological assessment of novel nitrofuranylamides as antituberculosis agents J. Antimicrob. Chemother. 62:1037-45
Yendapally, R, Hurdle, J.G, Carson, E. and Lee, R. (2008). N-Substituted 3-Acetyltetramic acid derivatives as antibacterial agents. J. Med. Chem. 51:1487-91.
Hurdle, J.G., O’Neill, A.J., and Chopra, I (2005). Prospects for aminoacyl-tRNA synthetase inhibitors as new antibacterial agents. Antimicrob. Agents and Chemother. 49, 4821-33.
Hurdle, J.G., O’Neill, A.J., Mody, L., Bradley, S.F. and Chopra, I. (2005). In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis. J. Antimicrob. Chemother. 56, 1166-8.
Hurdle, J.G., O’Neill, A.J. and Chopra, I. (2004). Anti-staphylococcal activity of indolmycin a potential topical agent for control of staphylococcal infections. J. Antimicrob. Chemother. 53, 549-52.
Hurdle, J.G., O’Neill, A.J. and Chopra, I. (2004). The isoleucyl-tRNA synthetase mutation V588F conferring mupirocin resistance in glycopeptide-intermediate Staphylococcus aureus is not associated with a significant fitness burden. J. Antimicrob. Chemother. 53, 102-4.
Hurdle, J.G., O’Neill, A.J., Ingham, E., Fishwick, C. and Chopra, I. (2004). Analysis of mupirocin resistance and fitness in Staphylococcus aureus by molecular genetic and structural modelling techniques. Antimicrobial Agents and Chemotherapy 48, 4366- 76.