Biology 3301-001, Cell Physiology, Spring 2007
 Mondays, Wednesday and Fridays 9:00-10:00 pm, Room CH 101
 

 

 

 

Instructor:                  Dr. Malgosia Wilk, M.D., Ph.D.  (M.A. Wilk-Blaszczak)

Office:                         LS 353

Laboratories:              LS 350/354

Office Hours:              Mon, Wed, Fri 10:00-11:00 am and Mon, Fri 12:00-1:00 pm or by appointment

Phone:                         (817) 272-7424

Mailbox:                     19498

Email:                          wilk@uta.edu

Web site:                    http://www.uta.edu/biology/wilk. Notes will be available for purchase from Grad Student Society Phi Sigma

 

Course Prerequisites:   BIOL 1441, 1442. CHEM 2181 and BIOL 3315 are recommended.

 

Required Textbook:     Cell Biology by T.D. Pollard and W.C. Earnshaw

 

Student learning outcomes:

1.   Understand the fundamental physiological mechanisms of cell function.

2.   Know the scientific methods that are currently being used to explore cell physiology.

 

Attendance and Drop Policy:

 

Attendance at lectures is required for success in this course. Attendance will be taken regularly during class time. Please be aware that lectures might cover material that is not included in the assigned readings. Per university policy, it is the student’s responsibility to initiate withdrawal from this course if they are doing poorly. Any student may withdraw with an automatic “W” at any time from the beginning of the semester to 3 days after the return of the first exam.

 

Reading Assignments:

 

Students are expected to read the assigned chapters prior to coming to class. The exams will draw heavily upon material discussed during lectures; however, students are still expected to master the material in the assigned chapters.

 

Exams:

 

Three semester exams, and a comprehensive final will determine your grade. All exams will be multiple choice. Exams will not be returned to students. Sample tests and/or old exams will not be made available. Examples of test questions will be presented in class in order to provide students with direction in their studies. The correct answers for the exams will be presented in the next scheduled class after the semester exams.

 

Exam I (30 multiple choice questions)

20%

Exam II (30 multiple choice questions)

20%

Exam III (30 multiple choice questions)

20%

Comprehensive Final (100 multiple choice questions)

40%

Total

100%

 

Grades: A = 90-100; B = 80-89; C = 70-79; D = 60-69; F = below 60.

TherE is No makeup for semester exams. In a case of missed semester exam your grade will be based on a comprehensive final (your final will account for 100% of your grade).  A makeup final exam will only be given for medical or emergency situations with a written proof. Incomplete grades may be assigned for a course if, in the opinion of the instructor, there are extenuating documented circumstances which prevent the student from completing the required work.  The incomplete must be removed by the end of the final examination period of the following semester, excluding the summer session, for the student to receive credit for the course.  If the incomplete is not removed during the allotted time it will revert automatically to an F.

 

Students are expected to:

1.       Attend class regularly, on time, and remain the entire class period.

2.       Stay abreast of all reading assigned in the course syllabus.

3.       Assume responsibility for their own learning.

4.       Adhere strictly to standards of academic honesty.

5.       Show respect to the instructor and fellow students at all times.

 

UT Arlington has adopted MavMail (e-mail) as an official means of communication with students. Students are required to check MavMail regularly.  Further information regarding your student email account can be found at:  http://www.uta.edu/oit/email/

 

Drop for non-payment of tuition: If you are dropped from this class for non-payment of tuition, you may secure an Enrollment Loan through the Bursar's Office. You may not continue to attend class until your Enrollment Loan has been applied to outstanding tuition fees.

 

Bomb Threats: If anyone is tempted to call in a bomb threat, be aware that UTA will attempt to trace the phone call and prosecute all responsible parties. Every effort will be made to avoid cancellation of presentations/tests caused by bomb threats. Unannounced alternate sites will be available for these classes. Your instructor will make you aware of alternate class sites in the event that your classroom is not available

 

Student Support Services: The University supports a variety of student success programs to help you connect with the University and academic success. They include learning assistance, development education, advising and mentoring, admission and transition, and federally funded programs. Students requiring assistance academically, personally, or socially should contact the Office of Student Success Programs at 817-272-6107 for more information and appropriate referrals.


Final Review Week: A period of five class days prior to the first day of final examinations in the long sessions shall be designated as Final Review Week. The purpose of this week is to allow students sufficient time to prepare for final examinations. During this week, there shall be no scheduled activities such as required field trips or performances; and no instructor shall assign any themes, research problems or exercises of similar scope that have a completion date during or following this week unless specified in the class syllabi. During Final Review Week, an instructor shall not give any examinations constituting 10% or more of the final grade, except makeup tests and laboratory examinations. In addition, no instructor shall give any portion of the final examination during Final Review Week.
  

Dropping a Course: If you decide to drop this course (or any other, for that matter) you must obtain a drop slip from the departmental undergraduate advisors office (for Biology, the advisor is Ms. Jane Pugh, Room 346 Life Science or you may go to the main office in the Biology Department 337 Life Science). Please fill it out, have the instructor of the course you wish to drop sign the slip and return it to the advisor's office or the Biology Office.


Academic Dishonesty: It is the philosophy of The University of Texas at Arlington that academic dishonesty is a completely unacceptable mode of conduct and will not be tolerated in any form. All persons involved in academic dishonesty will be disciplined in accordance with University regulations and procedures. Discipline may include suspension or expulsion from the University.

"Scholastic dishonesty includes but is not limited to cheating, plagiarism, collusion, the submission for credit of any work or materials that are attributable in whole or in part to another person, taking an examination for another person, any act designed to give unfair advantage to a student or the attempt to commit such acts."

 

Americans with Disabilities Act:

 

The university of Texas at Arlington is on record as being committed to both the spirit and letter of federal equal opportunity legislation: reference Public Law 93112--The Rehabilitation ''Act of 1973 as amended. With the passage of new federal legislation entitled Americans with Disabilities Act - (ADA), pursuant to section 504 of the Rehabilitation Act, there is renewed focus on providing this population with the same opportunities enjoyed by all citizens.


As a faculty member, I am required by law to provide "reasonable accommodation" to students with disabilities, so as not to discriminate on the basis of that disability. Student responsibility primarily rests with informing faculty at the beginning of the semester and in providing authorized documentation through designated administrative channels.

 

 

Week

Date

 

Lecture Topic

Text

1

Jan 17

First Class

Introduction, Principles of living cells

1

 

Jan 19

 

Cell structure, organelles

1

2

Jan 22

 

Molecular structures and function I

2

 

  Jan 24

 

Molecular structures and function II

2,4

 

Jan 26

 

Biomembranes structure and function

6

3

Jan 29

 

Exam I

 

 

Jan 31

Census Date

Exam review

 

 

Feb 02

 

Membrane transport – pumps

7

4

Feb 05

 

Oxidative phosphorylation

10

 

Feb 07

 

Membrane transport – carriers

8

 

Feb 09

 

Transport across epithelia

10

5

Feb 12

 

Membrane transport – ion channels

9

 

Feb 14

 

Ion channel function in excitable cells

10

 

Feb 16

 

Biogenesis – translation

17,18

6

Feb 19

 

Biogenesis - posttranslational targeting

19

 

Feb 21

 

Biogenesis – ER pathway

20

 

Feb 23

End of first drop

Biogenesis – ER processing, lipid synthesis

20

7

Feb 26

 

Vesicular traffic, exocytosis

21, 22

 

Feb 28

 

Endocytosis

23

 

Mar 02

 

Protein turnover

24

8

Mar 05

 

Exam II

 

 

Mar 07

 

Exam review

 

 

Mar 09

Midsemester

Overview of signaling

25

 

Mar 12-18

Spring Break

 

 

9

Mar 19

 

Receptors

26

 

Mar 21

 

Signaling hardware

27

 

Mar 23

 

   

10

Mar 26

 

Second messengers

28

 

Mar 28

 

Signaling software I -- Flash Movie File

29

 

Mar 30

Last Drop

Signaling software II

29

11

Apr 02

 

Signaling software III

29

 

Apr 04

 

Extracellular matrix

30,31

 

Apr 06

 

TBD

 

12

Apr 09

 

Cell adhesion

32

 

Apr 11

 

Cell junctions

33

 

Apr 13

 

Connective tissues

34

13

Apr 16

 

Cytoskeleton I – actin
35, 36

 

Apr 18

 

Cytoskeleton II – microtubules

37

 

Apr 20

 

Cytoskeleton III – intermediate filaments

38

14

Apr 23

 

Exam III

 

 

Apr 25

 

Motor proteins

39

 

Apr 27

 

Cell movement

40, 41

15

Apr 30

 

Muscle

42

 

May 02

 

Q and A

 

 

May 04

 

 

 

16