Dr. Perry N. Fuchs

Dr. Perry N. Fuchs

  • Professor of Psychology
  • Email: fuchs@uta.edu
  • Phone: (817) 272-9672
  • Address: Room 313, Life Sciences Bldg.
  • Website: Click to View
  • Description of Research

     

    A main focus of my overall research is aimed at exploring the basic, underlying central and peripheral nervous system mechanisms associated with rewarding and aversive stimuli. Experimental models, such as peripheral inflammation and neural injury, produce aversive behavioral responses that are associated with pain. A noxious stimulus usually engages specific peripheral mechanisms, causing several conscious sensations consisting of judgments regarding the location and extent of tissue damage. Typically, there is also an alteration in affect and an induction of subconscious somatic and autonomic responses. Using a variety of experimental models, central mechanisms of pain processing are elucidated using focal electrical stimulation, microinjection, and lesion techniques. Research on peripheral mechanisms focuses on the coupling between the sympathetic and somatic nervous system.

     

    Appointments and Education

     

    Professor - Departments of Psychology and Biology, 2013 - Present 
    Associate Professor - Departments of Psychology and Biology, 2004 - 2013 
    Associate Professor – Department of Psychology, 2003 – 2004
    Assistant Professor – Department of Psychology, 1998 – 2003

    B.S. – University of Calgary (Psychology)
    M.S. – University of Texas at Arlington (Psychology)
    Ph.D. - University of Texas at Arlington (Psychology)
    Post-Doctoral Research Fellow – McGill University (Psychology)
    Post-Doctoral Research Fellow – Johns Hopkins School of Medicine (Neurosurgery)

     

    Publications

     

    Journal Articles

    Kline, D. W., and Fuchs, P. The visibility of symbolic highway signs can be increased among drivers of all ages. Human Factors, 1993, 35, 25-34.

    Fuchs, P. N., and Cox, V. C. Habenula lesions attenuate lateral hypothalamic stimulation‑produced analgesia in the formalin test. Neuroreport, 1993, 4, 121-124.

    Fuchs, P. N., and Melzack, R. Analgesia induced by morphine microinjection into the lateral hypothalamus of the rat. Experimental Neurology, 1995, 134, 277-280.

    Lariviere, W. R., Fuchs, P. N., and Melzack, R. Hypophysectomy produces analgesia and paraventricular lesions have no effect on formalin‑induced pain. Experimental Neurology, 1995, 135, 74-79.

    Melzack, R., Germain, M., Bélanger, E., Fuchs, P. N., and Swick, R. Positive intra‑surgical suggestion fails to affect post‑surgical pain. The Journal of Pain and Symptom Management, 1996, 11, 103-107.

    Fuchs, P. N., Kerr, B., and Melzack, R. Delayed nociceptive response following cold‑water swim in the formalin test: Possible mechanisms of action. Experimental Neurology, 1996, 139, 291-298.

    Fuchs, P. N., and Melzack, R. Restraint reduces formalin‑test pain but the effect is not influenced by lesions of the hypothalamic paraventricular nucleus. Experimental Neurology, 1996, 139, 299-305.

    Fuchs, P. N., Lariviere, W. R., Balinsky, M., and Melzack, R. Acute amitriptyline treatment produces non‑opioid mediated analgesia in the formalin and bee venom test. Pathophysiology, 1996, 3, 227-331.

    Fuchs, P. N., Kerr, B., and Melzack, R. Possible non‑opioid mediated analgesia produced by methotrimeprazine in rats. Pain Research and Management, 1996, 1, 207-211.

    Fuchs, P. N., Balinsky, M., and Melzack, R. Electrical stimulation of the cingulum bundle and surrounding cortical tissue reduces formalin‑test pain in the rat. Brain Research, 1996, 743, 116-123.

    Fuchs, P. N., and Melzack, R. Repeated cold water swim produces delayed nociceptive responses, but not analgesia, for tonic pain in the rat. Experimental Neurology, 1997, 45, 303-307.

    Fuchs, P. N., and Gamsa, A. Chronic use of opioids for non‑malignant pain: A prospective study. Pain Research and Management, 1997, 2, 101-107.

    Melzack, R., and Fuchs, P. N. Pain, General. In: The Encyclopedia of Neuroscience, 2nd Edition (CD-ROM). Adelman, G. and Smith, B.H., eds. Amsterdam, Elsevier Science, 1997.

    Fuchs, P.N., Ringkamp, M., Shiotani, M., and Raja, S.N. Sympathectomy decreases formalin‑induced nociceptive responses independent of changes in peripheral blood flow. Experimental Neurology, 1999, 155, 95-102.

    Fuchs, P.N., Roza, C., Sora, I., Uhl, G., and Raja, S.N. Characterization of mechanical withdrawal responses and effects of mu, kappa and delta opioid agonists in normal and mu opioid receptor knockout mice. Brain Research, 1999, 821, 480-486.

    Fuchs, P.N., Pappagallo, M. and Meyer, R.A. Topical EMLA pre‑treatment fails to decrease the pain induced by 1% topical capsaicin. Pain, 1999, 80, 637-642.

    Melzack, R., and Fuchs, P. N. Pain, General. In: The Encyclopedia of Neuroscience, 2nd Edition. Adelman, G. and Smith, B.H., eds. Amsterdam, Elsevier Science, 1999, 1547-1550.

    Fuchs, P.N., Campbell, J.N., and Meyer, R.A. Secondary hyperalgesia persists in capsaicin desensitized skin. Pain, 2000, 84, 141-149.

    LaBuda, C.J., and Fuchs, P.N. A behavioral test paradigm to measure the aversive quality of inflammatory and neuropathic pain in rats. Experimental Neurology, 2000, 163, 490-494.

    LaBuda, C.J., Sora, I., Uhl, G.R., and Fuchs, P.N. Stress-induced analgesia in m-opioid receptor knockout mice reveals normal function of the d-opioid receptor system. Brain Research, 2000, 869, 1-5.

    LaBuda, C.J., Cutler, T.D., Dougherty, P.M., and Fuchs, P.N. Mechanical and thermal hypersensitivity develops following kainate lesion of the ventral posterior lateral thalamus in rats. Neuroscience Letters, 2000, 290, 79-83.

    LaBuda, C.J., and Fuchs, P.N. Morphine and gabapentin decrease mechanical hyperalgesia and escape/avoidance behavior in a rat model of neuropathic pain. Neuroscience Letters, 2000, 290, 137-140.

    Ali, Z., Raja, S.N., Wesselmann, U., Fuchs, P.N., Meyer, R.A., and Campbell, J.N. Intradermal injection of norepinephrine evokes pain in patients with sympathetically maintained pain. Pain, 2000, 88, 161-168.

    Fuchs, P.N. Beyond reflexive measures to examine higher order pain processing in rats. Pain Research & Management, 2000, 5, 215-219.

    LaBuda, C.J., and Fuchs, P.N. Aspirin attenuates the anxiolytic actions of ethanol. Alcohol, 2000, 21, 287-290.

    Fuchs, P.N., Raja, S.N., and Meyer, R.A. Topical capsaicin for the treatment of neuropathic pain. Analgesia, 2000, 5, 1-8.

    Fuchs, P.N., Meyer, R.A., and Raja, S.N. Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. Pain, 2001, 90, 15-23.

    Donahue, R.R., LaGraize, S.L., and Fuchs, P.N. Electrolytic lesion of the anterior cingulate cortex decreases inflammatory, but not neuropathic pain in rats. Brain Research, 2001, 897, 131-138.

    LaBuda, C.J., and Fuchs, P.N. A comparison of chronic aspartame exposure to aspirin on inflammation, hyperalgesia and open field activity following carrageenan-induced monoarthritis. Life Sciences, 2001, 69, 443-454.

    LaBuda, C.J., and Fuchs, P.N. Low dose aspirin attenuates escape/avoidance behavior, but does not reduce mechanical hyperalgesia in a rodent model of inflammatory pain. Neuroscience Letters, 2001, 304, 137-140.

    Kiser, R.S., Cohen, H.M., Freedenfeld, R.N., Jewell, C., and Fuchs, P.N. Olanzapine for the treatment of fibromyalgia symptoms. Journal of Pain Research and Management, 2001, 22, 704-708.

    LaBuda, C.J., and Fuchs, P.N. The anxiolytic effect of acute ethanol or diazepam exposure is unaltered in μ-opioid receptor knockout mice. Brain Research Bulletin, 2001, 55, 755-760.

    LaBuda, C.J., Donahue, R., and Fuchs, P.N. Enhanced formalin nociceptive responses following L5 ligation in the rat reveals neuropathy-induced inflammatory hyperalgesia. Pain, 2001, 94, 59-63.

    Magerl, W., Fuchs, P.N., Meyer, R.A., and Treede, R.-D. Roles of capsaicin-insensitive nociceptors in pain and secondary hyperalgesia. Brain, 2001, 124, 1754-1764.

    LaBuda, C.J., and Fuchs, P.N. Catecholamine depletion by reserpine blocks the anxiolytic actions of ethanol in the rat. Alcohol, 2002, 26, 55-59.

    Bencherif, B., Fuchs, P.N., Sheth, R., Dannals, R.F., Campbell, J.N., and Frost, J.J. Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET). Pain, 2002, 99, 589-598.

    Melzack, R., and Fuchs, P. N. Pain, General. In: The Encyclopedia of Neuroscience, 3rd Edition (CD-ROM). Adelman, G. and Smith, B.H., eds. Amsterdam, Elsevier Science, 2003.

    LaGraize, S.C., Borzan, J., and Fuchs, P.N. Decreased L5 spinal nerve ligation nociceptive behavior following L4 spinal nerve transection. Brain Research, 2003, 990, 227-230.

    Fuchs, P.N., and Peng, Y.B. Psychophysical evidence that central sensitization contributes to secondary hyperalgesia in human subjects. Seminars in Pain Medicine, 2003, 1, 132-138.

    LaGraize, S.C., LaBuda, C.J., Rutledge, M.A., Jackson, R.L., and Fuchs, P.N. Differential effect of anterior cingulate cortex lesion on mechanical hyperalgesia and escape/avoidance behavior in an animal model of neuropathic pain. Experimental Neurology, 2004, 188, 139-148.

    Borzan, J., LaGraize, S.C., and Fuchs, P.N. Effect of chronic vincristine treatment on mechanical withdrawal response and pre-pulse inhibition in the rat. Neuroscience Letters, 2004, 364, 110-113.

    Melzack, R., and Fuchs, P. N. Pain, General. In: The Encyclopedia of Neuroscience, 3rd Edition (CD-ROM). Adelman, G. and Smith, B.H., eds. Amsterdam, Elsevier Science, 2004.

    LaGraize, S.C., Borzan, J., Rinker, M.M., Kopp, J.L., and Fuchs, P.N. Behavioral evidence for competing motivational drives of nociception and hunger. Neuroscience Letters, 2004, 371, 30-34.

    Senapati, A.K., Huntington, P.J., LaGraize, S.C., Wilson, H.D., Fuchs, P.N., and Peng, Y.B. Electrical stimulation of the primary somatosensory cortex inhibits spinal dorsal horn neuronal activity. Brain Research, 2005, 1057, 134-140.

    Senapati, A.K., LaGraize, S.C., Huntington, P.J., Wilson, H.D., Fuchs, P.N., and Peng, Y.B. Electrical stimulation of the anterior cingulate cortex reduces responses of rat dorsal horn neurons to mechanical stimuli. Journal of Neurophysiology, 2005, 94, 845-851.

    LaBuda, C.J., and Fuchs, P.N. Attenuation of negative affect produced by unilateral spinal nerve injury in the rat following anterior cingulate cortex activation. Neuroscience, 2005, 136, 311-322.

    LaGraize, S.C., Borzan, J., Peng, Y.B., and Fuchs, P.N. Selective regulation of pain affect following activation of the opioid anterior cingulate cortex system. Experimental Neurology, 2006, 197, 22-30 (paper selected for press release and editorial comment by Rolf-Detlef Treede).

    Freedenfeld, R.N., Murray, M., Fuchs, P.N., and Kiser, S.K. Decreased pain and improved quality of life in fibromyalgia patients treated with olanzapine, an atyptical neuroleptic. Pain Practice, 2006, 6, 112-118.

    Wilson, H.D., Wilson, J.R., and Fuchs, P.N. Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain. Brain Research, 2006, 1098, 126-128.

    Gatchel, R.J., Peng, Y.B., Peters, M.L., Fuchs, P.N., and Turk, D. The biopsychosocial approach to chronic pain: scientific advances and future directions. Psychological Bulletin, in press.

    Borzan, J., and Fuchs, P.N. Testosterone facilitates morphine antinociception in carrageenan-induced inflammatory pain. Neuroscience, in press.

    Borzan, J., and Fuchs, P.N. Organizational and activational effects of testosterone on carrageenan-induced inflammatory pain and morphine analgesia. Neuroscience, 2006, 143, 885-893.

    Wilson , H.D., Boyette-Davis, J., and Fuchs, P.N. The relationship between basal level of anxiety and the affective response to inflammation. Physiology and Behavior, 2007, 506-511.

    LaGraize, S.C., and Fuchs, P.N. GABA A but not GABA B receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior. Experimental Neurology, 2007, 204, 182-194.

    Pool, G.J., Schwegler, A.F., Theodore, B.R., and Fuchs, P.N. Role of gender norms and group identification on hypothetical and experimental pain tolerance. Pain, 2007, 129, 122-129.

    Gatchel, R.J., Peng, Y.B., Peters, M.L., Fuchs, P.N., and Turk, D. The biopsychosocial approach to chronic pain: scientific advances and future directions. Psychological Bulletin, 2007, 133, 581-624.

    Wilson , H.D., Toepfer, V.E., Senapati, A.K., Wilson, J.R., and Fuchs, P.N. Hyperbaric oxygen treatment is comparable to acetylsalicylic acid treatment in an animal model of arthritis. The Journal of Pain, 2007, 12, 924-930.

    Boyette-Davis, J.A., Thompson, C.D., Fuchs, P.N. Alterations in attentional mechanisms in response to acute inflammatory pain. Neuroscience, 2008, 151, 558-563.

    Wilson , H.D., Uhelski, M.L., and Fuchs, P.N. Examining the role of the medial thalamus in modulating the affective dimension of pain. Brain Research, in press.

     

    Book Chapters and other publications

    Fuchs, P.N., Roza, C., Sora, I., Uhl, G., and Raja, S.N. Characterization of mechanical withdrawal responses and effects of mu, kappa and delta opioid agonists in normal and mu opioid receptor knockout mice. Protein Research Foundation Database, 1999, http://www.prf.or.jp/, PRF/LITDB, accession number 2508912.

    Jørum, E., Warncke, T., Ziegler, E.A., Magerl, W., Fuchs, P.N., Meyer, R.A., and Treede, R.-D. Secondary hyperalgesia to punctate stimuli is mediated by A-fiber nociceptors. In: Proceedings of the 9th World Congress on Pain, Progess in Pain Research and Management, Devor, M., Rowbotham, M.C. and Wiesenfeld-Hallin, Z., eds. Seattle, IASP press, 2000, 215-223.

    Fuchs, P.N., and Kinzler, D. Morphine microinjection into the anterior cingulate cortex and the decrease of inflammatory pain in the rat. In: The University of Texas at Arlington McNair Research Journal, Arlington, The University of Texas at Arlington, 2000, 124-131.

    Fuchs, P.N., Lee, J.I., and Lenz, F.A. Central pain secondary to intracranial injury. In: Pain Surgery, Kim J. Burchiel (Ed)., Thieme, 2001.

    Allen, C., Fuchs, P.N., Shriver, A., and Wilson, H.D. Deciphering animal pain. Pain: New Essays on its Nature and the Methodology of its Study. Murat Aydede, Ed., MIT Press, 2005, 351-366.

    Peng, Y.B., Fuchs, P.N., and Gatchel, R.J. Chronic pain: the diathesis-stress model. In: Stress in Health and Disease, B.B. Arnetz and R. Ekman (Eds), Wiley-VCH Verlag, Germany, 2006, 333-341.

    Fuchs, P.N., and Peng, Y.B. Thalamotomy and behavior in animals. Encyclopedic Reference of Pain, submitted.

    Fuchs, P.N., and Cox, V.C. Nociceptive processing in the cingulate cortex: behavioral studies in animals. Encyclopedic Reference of Pain, submitted.

    Gatchel, R.J., Fuchs, P.N., and Allen, C. Ethical issues in chronic pain research. In: Ethical Issues in Chronic Pain Management. M.E. Schatman and B.L. Gant, Eds., Taylor & Francis, submitted.

     

    Abstract and Paper Presentations:

    Fuchs, P. N., and Cox, V. C. Habenula lesions attenuate lateral hypothalamic stimulation‑produced analgesia in the formalin test. Society for Neuroscience Abstracts, 1992, 18, 684.

    Fuchs, P. N., and Cox, V. C. The effect of lateral hypothalamic stimulation on tail‑flick and both phases of the formalin pain response. Society for Neuroscience Abstracts, 1993, 19, 964.

    Fuchs, P. N. Differential effect of lateral hypothalamic stimulation on tail‑flick and first period of the formalin nociceptive response. Psi Chi 5th Annual Student's Convention, Texas Christian University and Southwestern University, February 18-19, 1994.

    Fuchs, P. N., and Melzack, R. Delayed nociceptive response following cold water swim. Canadian Pain Society Annual Meeting, Ottawa, 1995

    Fuchs, P. N., and Melzack, R. Differential effects of paraventricular nucleus lesions on stress‑induced analgesia during the first and second phase of the formalin test. Society for Neuroscience Abstracts, 1995, 21, 646.

    Fuchs, P. N., and Melzack, R. Cingulum bundle stimulation produces analgesia for tonic pain in the rat. 8th World Congress on Pain, Vancouver, BC, Canada, August 17-22, 1996.

    Meyer, R.A., Fuchs, P.N., and Raja, S.N. Intradermal norepinephrine and phenylephrine produces a dose dependent hyperalgesia to heat in humans. 8th World Congress on Pain, Vancouver, BC, Canada, August 17-22, 1996.

    Fuchs, P.N., Balinsky, M., and Melzack, R. Stimulation of the cingulum bundle and surrounding cortical tissue: Effect on tonic pain in the rat. Society for Neuroscience Abstracts, 1996, 22, 116.

    Fuchs, P.N., Ringkamp, M., and Raja, S.N. Surgical sympathectomy decreases formalin‑induced pain but does not alter paw‑withdrawal thresholds to mechanical stimuli in rats. Society for Neuroscience Abstracts, 1997, 23, 2356.

    Fuchs, P.N., Roza, C., Sora, I., Uhl, G.R., and Raja, S.N. Morphine fails to alter paw withdrawal thresholds to mechanical stimuli in m‑opiate receptor knockout mice. American Pain Society, 16th Annual Scientific Meeting, New Orleans, LA, USA, October 23-26, 1997.

    Fuchs, P.N., Pappagallo, M., and Meyer, R.A. Topical anesthesia does not eliminate pain to topical capsaicin. American Pain Society, 16th Annual Scientific Meeting, New Orleans, LA, USA, October 23-26, 1997 (*Citation Poster).

    Oropeza, M., Fuchs, P.N., Bensherif, B., Li, S., Ravert, H., Musachio, J., Mathews, B., Campbell, J.N., and Frost, J. The effect of capsaicin‑induced pain on human brain mu opioid receptor binding measured by PET. Society of Nuclear Medicine, 45th Annual Meeting, Toronto, Ontario, Canada, June 7-11, 1998.

    Oropeza, M., Fuchs, P.N., Bensherif, B., Li, S., Ravert, H., Musachio, J., Mathews, B., Campbell, J.N., Dannals, B., and Frost, J. Modulation of human brain mu opioid receptor binding during capsaicin‑induced pain measured by PET. Neuroreceptor Mapping 98, Ann Arbour, Michigan, USA, June 13-15, 1998.

    Sora, I., Hall, S., Wang, Z., Fuchs, P., Li, F‑X., Kitanaka, N., Zeng, Z., Raja, S.N., and Uhl., G.R. Mu opiate receptor genes, nociception and reward: potential lessons in knockout mice, mouse strains and humans. 29th International Narcotics Research Conference, Garmisch‑Partenkirchen, Germany, July 20-25, 1998.

    Shiotani, M., Fuchs, P.N., Ringkamp, M., Mansikka, H., Brimijoin, S., Hammond, P., and Raja, S.N. Preganglionic immunosympathectomy decreases formalin‑induced pain but does not alter mechanical paw‑withdrawal thresholds in rats. Society for Neuroscience Abstracts, 1998, 24, 2084.

    Fuchs, P.N., Roza, C., Sora, I., Ujike, H., Uhl, G., and Raja, S.N. Differential effects of mu, delta, and kappa‑opioid receptor agonists on the response to mechanical stimuli in mu‑opioid receptor knockout mice. Society for Neuroscience Abstracts, 1998, 24, 888.

    Huang, J.H., Fuchs, P.N., Roza, C., Ali, Z., Campbell, J.N., and Meyer, R.A. Pain ratings to punctate mechanical stimuli in secondary hyperalgesia zone produced by capsaicin injection are dose ‑dependent. Society for Neuroscience Abstracts, 1998, 24, 2085.

    Raja, S.N., Fuchs, P.N., and Meyer, R.A. Heat hyperalgesia in humans following intradermal injections of a1 and a2 agonists. Society for Neuroscience Abstracts, 1998, 24, 1631.

    Magerl, W., Fuchs, P.N., Meyer, R.A., and Treede, R.D. Pain to punctate mechanical stimuli in humans is mainly mediated by capsaicin‑insensitive A‑fiber nociceptors. Society for Neuroscience Abstracts, 1998, 24, 2085.

    Meyer, R.A., Magerl, W., Campbell, J.N., Treede, R.D., and Fuchs, P.N. Normal punctate hyperalgesia in capsaicin desensitized skin. Society for Neuroscience Abstracts, 1998, 24, 2086.

    Oropeza, M., Fuchs, P.N., Bensherif, B., Li, S.T., Ravert, H., Musachio, J., Mathews, B., Dannals, B., Campbell, J.N., Belzberg, A., and Frost, J.J. The effect of capsaicin‑induced pain on human brain mu opioid receptor binding measured by PET. Society for Neuroscience Abstracts, 1998, 24, 528.

    Shiotani, M., Fuchs, P.N., Ringkamp, M., Mansikka, H., Brimijoin, S., Hammond, P., and Raja, S.N. Preganglionic immunosympathectomy decreases formalin‑induced pain but does not alter mechanical paw‑withdrawal thresholds in rats. American Pain Society, 17th Annual Scientific Meeting, San Diego, CA, USA, November 5-8, 1998.

    Huang, J.H., Fuchs, P.N., Roza, C., Ali, Z., Campbell, J.N., and Meyer, R.A. Pain ratings to punctate mechanical stimuli in secondary hyperalgesia zone produced by capsaicin injection are dose ‑dependent. American Pain Society, 17th Annual Scientific Meeting, San Diego, CA, USA, November 5-8, 1998.

    Raja, S.N., Fuchs, P.N., and Meyer, R.A. Heat hyperalgesia in humans following intradermal injections of a1 and a2 agonists. American Pain Society, 17th Annual Scientific Meeting, San Diego, CA, USA, November 5-8, 1998.

    Magerl, W., Fuchs, P.N., Meyer, R.A., and Treede, R.‑D. Pain to punctate mechanical stimuli in humans is mainly mediated by capsaicin-insensitive A-fiber nociceptors. American Pain Society, 17th Annual Scientific Meeting, San Diego, CA, USA, November 5-8, 1998.

    Meyer, R.A., Magerl, W., Campbell, J.N., Treede, R.‑D., and Fuchs, P.N. Normal punctate hyperalgesia in capsaicin desensitized skin. American Pain Society, 17th Annual Scientific Meeting, San Diego, CA, USA, November 5-8, 1998.

    Magerl, W., Ziegler, E.A., Fuchs, P.N., Meyer, R.A., and Treede, R.-D. Cutaneous pain and hyperalgesia to punctate stimuli in humans is mediated by capsaicin-insensitive A-fiber nociceptors. Symposium of Spinal Cord Plasticity, Los Angeles, CA, USA, November 7, 1998.

    Bencherif, B., Oropeza, M., Fuchs, P.N., Sheth, R., Li, S.T., Ravert, H., Musachio, J., Mathews, B., Dannals, B., Campbell, J.N., and Frost, J.J. Regional mu opioid receptor binding changes in healthy controls following capsaicin-induced pain and their relationships to pain intensity. International Society of Cerebral Blood Flow and Metbolism, Copenhagen, Denmark, June 13–17, 1999.

    Bencherif, B., Oropeza, M., Fuchs, P.N., Sheth, R., Li, S.T., Ravert, H., Musachio, J., Mathews, B., Dannals, B., Campbell, J.N., and Frost, J.J. PET scan analysis of mu opioid receptor binding during a tonic painful stimulus in normal human subjects. 9th World Congress on Pain, Vienna, Austria, August 22-27, 1999.

    Magerl, W., Fuchs, P.N., Meyer, R.A., and Treede, R.-D. Secondary hyperalgesia to punctate stimuli in humans is mediated by capsaicin-insensitive A-fiber nociceptors. 9th World Congress on Pain, Vienna, Austria, August 22-27, 1999.

    LaBuda, C.J., and Fuchs, P.N. Place aversion paradigm: a simple method for measuring pain in neuropathic and inflammatory animal models. 9th World Congress on Pain, Vienna, Austria, August 22-27, 1999.

    LaBuda, C.J., and Fuchs, P.N. The place avoidance paradigm as a method to measure affect following nerve injury and inflammatory induced hyperalgesia in rats. Society for Neuroscience Abstracts, 1999, 25, 687.

    LaGraize, S.C., LaBuda, C.J., Donahue, R.R., Rutledge, M.A., Jackson, R.A., and Fuchs, P.N. Cingulate cortex lesions attenuate escape/avoidance behavior but have no effect on hyperalgesia following L5 ligation in rats. Society for Neuroscience Abstracts, 2000, 26, 650.

    LaBuda, C.J., Donahue, R.R., LaGraize, S.C., and Fuchs, P.N. Lesions of the cingulate cortex decrease inflammatory, but not neuropathic pain in rats. Society for Neuroscience Abstracts, 2000, 26, 650.

    Bencherif, B., Fuchs, P.N., Sheth, R.N., Oropeza, M., Musachio, J.L., Mathews, B., Dannals, R.F., Campbell, J.N., and Frost, J.J. Acute pain activation of supraspinal opioid pathways shown with positron emission tomography in humans. Society for Neuroscience Abstracts, 2000, 26, 1593.

    LaBuda, C.J., and Fuchs, P.N. Catecholamine depletion blocks the anxiolytic actions of ethanol. Southwestern Psychological Association, 2001, Houston, TX.

    LaBuda, C.J., and Fuchs, P.N. Ethanol or diazepam’s anxiolytic actions in μ-opioid receptor knockout mice. Southwestern Psychological Association, 2001, Houston, TX.

    LaBuda, C.J., and Fuchs, P.N. Low dose aspirin attenuates escape/avoidance behavior, but does not reduce mechanical hyperalgesia in a rodent model of inflammatory pain. The Journal of Pain, 2001, 2 (suppl 1), 22. Presented at the American Pain Society, Phoenix, AZ.

    LaGraize, S.C., LaBuda, C.J., Borzan, J., and Fuchs, P.N. Reducing the aversive quality of nociception by activation or deactivation of the anterior cingulate cortex in the rat. Society for Neuroscience, 2001, San Diego, CA.

    LaGraize, S.C., Borzan, J., and Fuchs, P.N. Decreased pain affect following morphine microinjection into the cingulate cortex. Southwestern Psychological Association, 2002, Corpus Cristi, TX.

    Freedenfeld, R.N., Bailey, B.E., Bruns, D., Fuchs, P.N., and Kiser, R.S. Prediction of interdisciplinary pain treatment outcome using the Battery for Health Improvement. 10th World Congress on Pain, San Diego, CA, August 17-22, 2002.

    LaGraize, S.C., Borzan, J., Peng, Y.B., and Fuchs, P.N. Morphine injection into the anterior cingulate cortex selectively modulates pain affect. 10th World Congress on Pain, San Diego, CA, August 17-22, 2002.

    LaGraize, S.C., Borzan, J., King, V.A., Peng, Y.B., and Fuchs, P.N. Low dose systemic morphine selectively modulates pain affect. Society for Neuroscience, 2002, Orlando, FL.

    Borzan, J., LaGraize, S.C., Fuchs, P.N., and Peng, Y.B. Dorsal horn neuron response patterns to graded heat stimuli in rat. Society for Neuroscience, 2002, Orlando, FL.

    Pool, G., Woo, A., Schwegler, A., and Fuchs, P. Group identification and conformity to gender group norms for pain tolerance. SPSP, 2002, Los Angeles, CA.

    Robertson, T., LaGraize, S., Borzan, J., Maddox, J., and Fuchs, P. Central pain syndrome exhibited in the rat model. Sigma Xi, 2002, Galveston TX.

    LaGraize, S.C., Borzan, J., King, V.A., and Fuchs, P.N. Decreased pain affect following low dose systemic morphine administration. Southwestern Psychological Association, 2003, New Orleans, LA.

    Schwegler, A.F., Pool, G.J., Fuchs, P.N., and Woo, A.N. Gender identification and conformity to gender norms for pain tolerance. Southwestern Psychological Association, 2003, New Orleans, LA.

    Rinker, M.M., Noska, K.D., Borzan, J., LaGraize, S.C., Peng, Y.B., Fuchs, P.N. Impaired sensory and motor functioning in acute encephalomyelitis: An animal model of multiple sclerosis. University of Texas Psychology Convention, March 7–8, 2003.

    Borzan, J., LaGraize, S.C., Peng, Y.B., and Fuchs, P.N. Testosterone facilitates morphine antinociception in carrageenan induced inflammatory pain. Society for Neuroscience, 2003, New Orleans, LA.

    LaGraize, S.C., Borzan, J., Peng, Y.B., and Fuchs, P.N. Effect of GABA microinjection in the rostral anterior cingulate cortex on supraspinal processing of nociception. Society for Neuroscience, 2003, New Orleans, LA.

    Fuchs, P.N., LaGraize, S.C., Borzan, J., Kongsamut, S., and Smith, C.P. Effectiveness of oral ion channel antagonist, HP184, in a neuropathic pain model. Society for Neuroscience, 2003, New Orleans, LA.

    Peng, Y.B., and Fuchs, P.N. Dorsal root has a faster conduction velocity than the peripheral nerve. Society for Neuroscience, 2003, New Orleans, LA.

    LaGraize, S.C., Borzan, J., Waldo, H., Peng, Y.B., and Fuchs, P.N. Morphine and GABA administration in the rostral anterior cingulate cortex alters supraspinal processing of nociception. American Pain Society, 2004, Vancouver, Canada.

    Pool, G.J., Schwegler, A.F., LaGraize, S.C., and Fuchs, P.N. Influence of group identification and conformity to gender group norms on pain tolerance. American Pain Society, 2004, Vancouver, Canada.

    Senapati, A.K., LaGraize, S.C., Waldo, H.D., Fuchs, P.N., and Peng, Y.B. Spinal dorsal horn neuron response to mechanical stimuli is decreased by stimulation of the primary motor and somatosensory cortices. American Pain Society, 2004, Vancouver, Canada.

    Peng, Y.B., Senapati, A.K., LaGraize, S.C., Waldo, H., and Fuchs, P.N. Electrical stimulation of the anterior cingulate cortex reduces responses of rat dorsal horn neurons to mechanical stimuli. American Pain Society, 2004, Vancouver, Canada.

    LaGraize, S.C., Wilson, H.D., and Fuchs, P.N. GABAA microinjected into the rostral anterior cingulate cortex effects supraspinal processing of nociception. Society for Neuroscience, 2004, San Diego, CA.

    LaGraize, S., Kopp, J., Fuchs, P., and Arellano, D. Barholding during acute pain in the laboratory rat. Association for Behavior Analysis, 2005, Chicago, IL.

    Kachlic, L., and Fuchs, P.N. Pain processing in an autistic animal model. Annual Celebration of Excellence by Students, University of Texas at Arlington, 2005.

    Trevino, K., and Fuchs, P.N. Balance of homeostasis: Competing motivations of hunger and nociception. Annual Celebration of Excellence by Students, University of Texas at Arlington, 2005.

    Peng, Y.B., Fuchs, P.N., LaGraize, S.C., Borzan, J., and Senapati, A.K. Increased behavioral and electrophysiological responses to mechanical stimuli in Experimental Autoimmune Encephalomyelitis (EAE). Society for Neuroscience, 2005, Washington, D.C.

    Weaver, R.R., Hagains, C.E., Davis, J.A., Wilson, H.D., Peng, Y.B., and Fuchs, P.N. Increased sensitivity to mechanical stimulation in an animal model of multiple sclerosis. Southwestern Psychological Association, 2006, Austin, TX.

    *Fuchs, P.N. Contribution of the cingulate cortex to pain processing. NIH Pain Consortium Symposium, April 17 & 18, 2006, Bethesda, MD. (by invitation only).

    He, J.-W., Fuchs, P.N., and Peng, Y.B. Stimulation of anterior cingulate cortex inhibits spinal dorsal horn neuron response to peripheral formalin injection. Society for Neuroscience, 2006, Atlanta, submitted.

    Wilson, H.D., Toepfer, V.E., Senapati, A.K., Wilson, J.R., and Fuchs, P.N. Hyperbaric oxygen treatment decreases edema and mechanical hypersensitivity in animal models of acute inflammation and arthritis. Society for Neuroscience, 2006, Atlanta.

    Boyette-Davis, J.A., Thompson, C.D., Wilson, H.D., and Fuchs, P.N. The impact of pain on attentional processing. Society for Neuroscience, 2006, Atlanta.

    Uhelski, M.L., Barnes, J.L., Thompson, C.D., Boyette-Davis, J.A., and Fuchs, P.N. Role of the medial dorsal thalamus in pain processing. Southwestern Psychological Association, 2007, Fort Worth, TX.

    Boyette-Davis, J.A., and Fuchs, P.N. Increased impulsivity in rats administered methylphenidate. Southwestern Psychological Association, 2007, Fort Worth, TX.

    Thompson, C.D., Boyette-Davis, J.A., Uhelski, M.L., and Fuchs, P.N. The effect of lesions to the insular cortex on fear and pain processing. Southwestern Psychological Association, 2007, Fort Worth, TX.

    Uhelski, M.L., Barnes, J.L., Thompson, C.D., Boyette-Davis, J.A., and Fuchs, P.N. Role of the medial dorsal thalamus in pain processing. Annual Celebration of Excellence by Students, University of Texas at Arlington, 2007.

    Thompson, C.D., McKenna, J.E., Hagains, C.E., Boyette-Davis, J.A., Peng, Y.B., and Fuchs, P.N. The synthetic marijuana drug, WIN-55,212-2, improves motor deficits in a model of Multiple Sclerosis. Annual Celebration of Excellence by Students, University of Texas at Arlington, 2007.

    Boyette-Davis, J.A., and Fuchs, P.N. Decrements in attentional mechanisms in response to acute pain. Annual Celebration of Excellence by Students, University of Texas at Arlington, 2007.

    Fuchs, P.N., Boyette-Davis, J.A., Thompson, C.D., and Uhelski, M.L. Recent advances in underlying mechanisms of pain and attention. Research Day, University of Texas at Arlington, 2007.

    Boyette-Davis, J.A., Thompson, C.D., Uhelski, M.L., and Fuchs, P.N. Methylphenidate administration during the five choice serial reaction time task: a strain comparison in Sprague Dawley and Long Evans rats. Society for Neuroscience, 2007, San Diego, CA.

    Boyette-Davis, J.A., Uhelski, M.L, and Fuchs, P .N. Differential Effects of Methylphenidate Administration in Sprague Dawley and Long Evans Rats. University of Texas at Arlington Psi Chi Annual Conference, 2008, Arlington, TX.

    Uhelski, M.L., Boyette-Davis, J.A., and Fuchs, P.N. Evaluating the effects of naltrexone on affective pain processing in the place escape avoidance paradigm. Annual Celebration of Excellence by Students, University of Texas at Arlington, 2008.

     


    Invited Presentations

     

     

    Link between physiological and psychological aspects of pain. Medical Grand Rounds, Montreal General Hospital, Montreal, March 20, 1995.

    Mechanisms of primary and secondary hyperalgesia. Blaustein Pain Treatment Center Conference, Johns Hopkins Hospital, November 14, 1997.

    Topical capsaicin and neuropathic pain. Blaustein Pain Treatment Center Conference, Johns Hopkins Hospital, January 30, 1998.

    Supraspinal mechanisms of pain. University of Texas at Arlington, Department of Psychology, March 11, 1998.

    Opioid receptors and pain: Studies in mu knockout mice. Blaustein Pain Treatment Center Conference, Johns Hopkins Hospital, April 17, 1998.

    Behavioral analysis of the aversive nature of nociception in the rat. MD Anderson Cancer Center, May 4, 2000.

    Chemotherapy-induced cognitive impairment. MD Anderson Cancer Center, March 24, 2001.

    Beyond reflexive measures in animal models of neuropathic and inflammatory pain. Aventis, New Jersey, August 2002.

    Differentiating sensory/discriminative versus affective/motivational pain processing in rats using a novel behavioral paradigm. The University of Kansas Medical Center, January 2003.

    Pain processing in experimental autoimmune encephalomyelitis. Research Symposium, North Texas Chapter of the National Multiple Sclerosis Society, Harris Methodist Hospital, Fort Worth, TX, October 2003.

    The debate to legalize marijuana. Moderator, Sponsored by EX.C.E.L. campus activities, University of Texas at Arlington, November 6, 2003.

    Health Professions Advisory Committee. Medical Dental Preparatory Association, University of Texas at Arlington, February 11, 2004.

    Behavioral studies of supraspinal pain processing. Texas A&M University, February, 2004.

    Stop pain. UTA Today television series (Comcast Cable), June, 2004.

    Neurobiology of pain. Biological Society, University of Texas at Arlington, November, 2004.

    The cingulate cortex and pain. Department of Biological Sciences, University of North Texas, December, 2004.

    Neuropharmacology of Pain. Advances in Chronic Pain Management, University of Texas at Arlington and University of Texas Southwestern Medical School Symposium, February 4, 2005.

    Modulation of higher order pain processing by the anterior cingulate cortex. Texas Christian University, March 28, 2005.

    Cognitive Impairment. Mechanisms and Treatment of Cancer-Related Symptoms, The University of Texas M.D. Anderson Cancer Center, September 10, 2005.

    Behavioral Measurements of Higher-Order Cognitive Function in Rodents. Mechanisms and Treatment of Cancer-Related Symptoms, The University of Texas M.D. Anderson Cancer Center, September 11, 2005.

    The Anterior Cingulate Cortex and Higher Order Pain Processing. Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, November 1, 2005.

    Neuroscience, Pain, and Health Psychology. Department of Psychology and Counseling, Tarleton State University, November 14, 2007.

     

     

    Recommended Sites

     

    Society for Neuroscience
    International Association for the Study of Pain
    American Pain Society
    Canadian Pain Society

    Undergraduate Research Assistant Application for Dr. Perry Fuchs


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    Address:

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