Modeling dysfunction of
the prefrontal executive system.
The concept of executive function in the brain is given
a new definition, as based in a distributed neural system whereby prefrontal
cortex is interconnected with various other cortical and subcortical loci.
Executive function is divided roughly into three interacting parts: affective
guidance of response; establishing linkage among working memory representations;
and forming complex behavioral schemata. Neural network models of
these parts are reviewed and fit into a preliminary theoretical framework.